Paraganglioma of the posterior mediastinum: Value of magnetic resonance imaging

Tanaka, Fumihiro; Kitano, Morihisa; Tatsumi, Akitoshi; Huang, Cheng-long; Nagasawa, Miyuki; Mino, Masaki; Matsuo, Michimasa; Ichijima, Kunio

doi:10.1016/0003-4975(92)90284-b

Cited by 19 publications

(17 citation statements)

References 6 publications

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“…3,4 The posterior mediastinum is the most common origin of intrathoracic PCs, as reviewed over the past several years. [1][2][3] Although most PCs are catecholamine-secreting, hyperfunctioning tumors, approximately 17% of the patients remain asymptomatic while bearing potentially unstable endocrine tumors, as in the present case. 4 The lack of an endocrinological study limits any discussion of the possible mechanisms that might have preoperatively suppressed the hyperfunction in our case.…”

Section: Discussionmentioning

confidence: 99%

“…1 Extraadrenal PC, also referred to as paraganglioma, is a rare entity that accounts for approximately 10% of PCs in adults. 2,3 The intrathoracic site is the rarest and accounts for less than 1% of the sites in which PCs can arise. 3,4 The posterior mediastinum is the most common origin of intrathoracic PCs, as reviewed over the past several years.…”

Section: Discussionmentioning

confidence: 99%

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Pheochromocytoma of the posterior mediastinum undiagnosed until the onset of intraoperative hypertension

Sakamaki

Yasukawa

Kido

2008

Gen Thorac Cardiovasc Surg

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An asymptomatic 42-year-old man was diagnosed with a posterior mediastinal mass, most likely a nonfunctioning, benign, neurogenic tumor for which thoracoscopic surgery was initially indicated. However, the systemic blood pressure rapidly increased to a critical level immediately after starting the surgical manipulation of the tumor, which was suggestive of a hyperfunctioning pheochromocytoma. The tumor was removed after controlling the blood pressure and was histologically diagnosed as a pheochromocytoma. The patient had an uneventful course, and the tumor was proven to be sporadic through further postoperative investigations. The possibility of extraadrenal pheochromocytoma should be considered in the preoperative diagnosis of an intrathoracic paraaortic tumor, even in an asymptomatic patient.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Pheochromocytoma of the posterior mediastinum undiagnosed until the onset of intraoperative hypertension

Sakamaki

Yasukawa

Kido

2008

Gen Thorac Cardiovasc Surg

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“…Magnetic resonance imaging (MRI) is superior to CT to evaluate the extent of the mediastinal tumor because the coronal, sagittal as well as axial magnetic resonance images enable determination of overall tumor extent and good contrast of soft tissues and vessels. In addition, MRI is noninvasive and safely provides the information about the vascularity of tumor as flow void [7]. Mediastinal tumors with high vascularity are limited to only four entities: Castleman's disease, hemangioma, goiter and paraganglia [6].…”

Section: Discussionmentioning

confidence: 99%

A rare cause of hypertension in children: intrathoracic pheochromocytoma

Singh

Rana²,

Sharma

et al. 2008

Pediatr Surg Int

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Mediastinal pheochromocytomas account for only a small fraction of mediastinal tumors. Most commonly, these tumors are located in posterior mediastinum. Increasing number of cases of pheochromocytomas is being reported from middle mediastinum. Excision of mediastinal paraganglioma is often hazardous because of its rich blood supply and tendency to involve surrounding structures. It can be a big challenge to manage asymptomatic cases of pheochromocytoma intraoperatively. It is imperative that these patients receive adequate alpha adrenergic and if necessary beta adrenergic blockade. Adequate preoperative preparation with alpha and beta blockers may not prevent serious intraoperative hypertension. We report a case of posterior mediastinal pheochromocytoma which was biochemically active preoperatively. We review the presentation, diagnosis and management of intrathoracic pheochromocytomas including cardiac pheochromocytomas.

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“…The MR appearance of mediastinal paraganglioma has been described in a limited number of case reports. The tumor was described as having a homogeneous texture; however, the T 1weighted and T 2-weighted imaging findings of the tumor, as well as imaging parameters used for MR imaging, were not mentioned in most of the reported cases [6][7][8][9].…”

Section: Discussionmentioning

confidence: 99%

“…Differentiation of malignant mediastinal paragangliomas with obvious vascular invasion and known metastases from other malignant mediastinal masses appears to be not possible, because the signal characteristics of many solid tumors are similar and there are no specific signal characteristics which permit MR differentiation of the specific histologic type [7,8].…”

Section: Discussionmentioning

confidence: 99%

Magnetic resonance imaging findings of a nonfunctional mediastinal paraganglioma with an unusual presentation

et al. 1997

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A case of histologically proven mediastinal paraganglioma presenting with metastatic spread to supraclavicular lymph nodes is presented. Mediastinal paragangliomas are extremely rare tumors and their CT and MR imaging features have not been well documented in the radiologic literature. The T 1-weighted and T 2-weighted spin-echo MR findings of a locally invasive mediastinal paraganglioma with metastasis to the supraclavicular lymph nodes are described and the literature is briefly reviewed.

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Paraganglioma of the posterior mediastinum: Value of magnetic resonance imaging

Cited by 19 publications

References 6 publications

Pheochromocytoma of the posterior mediastinum undiagnosed until the onset of intraoperative hypertension

Pheochromocytoma of the posterior mediastinum undiagnosed until the onset of intraoperative hypertension

A rare cause of hypertension in children: intrathoracic pheochromocytoma

Magnetic resonance imaging findings of a nonfunctional mediastinal paraganglioma with an unusual presentation

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