Paraffin Histology Sections and Delayed Repair in Recurrent Atypical Fibroxanthoma of the Eyelid

Abstract

We present a report of a recurrent atypical fibroxanthoma (AFX), a tumour known rarely to involve the eyelid. A 61 year-old male was referred after reappearance of a lower eyelid AFX within two months of resection. The neoplastic spindle cells at the periphery of an AFX may be difficult to differentiate from dermal fibroblasts in frozen sections. Paraffin sections provide better histological definition and thus greater accuracy in determining completeness of excision. The patient's recurrent tumour was surgically excised and overnight paraffin sections were used to obtain margin clearance, before secondary reconstruction. The tumour required re-excision on three occasions before clearance was achieved. The patient remains tumour free at 12 months' follow-up.

Atypical fibroxanthoma management: Recurrence, metastasis and disease‐specific death

“…In a separate analysis, recurrences from case series and case reports were tabulated (Table ). There were 101 recurrences reported in the literature, 87 were treated with LE or WLE, 13 were treated with MMS and 1 did not specify the mode of treatment.…”

Atypical Fibroxanthoma of the Medial Canthus: A Rare Presentation

“…7 There has been only one reported case of recurrence of AFX of the eyelid. 8 Invasion beyond the dermis and a rapid rate of recurrence are suggestive of a more aggressive clinical course. Our case appeared to show fast and aggressive growth of the mass following initial excision, but there was no evidence of recurrence on further excision.…”

Atypical Fibroxanthoma of the Bulbar Conjunctiva: A Unique Case Describing the Pathology, Clinical Presentation, and Management

“…Data on recurrence in ocular lesions is limited, however. There are a few case reports of recurrent atypical fibroxanthoma of the eyelid and limbus [14,15]. Follow-up is recommended annually for monitoring of recurrence.…”