Paradigms of modern epileptology

Badalian, Oganes L.; Burd, Sergei G.; Лебедева, А. В.; Avakian, Georgii G.; Oleinikova, Olga M.; Savenkov, A. A.

doi:10.26442/20751753.2021.2.200738

Cited by 2 publications

(2 citation statements)

References 199 publications

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“…. Estimated in the same way as in [28,35] for the 1P scalar state one has R ′ 1P (0) = 0.086 GeV 5/2 , ω 1 = ω 2 = 0.448 GeV [44] and according to (A1.6) one obtains (f…”

Section: Appendix A1 Decay Constants Of Scalar Mesonsmentioning

confidence: 95%

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Scalar mesons in the chiral theory with quark degrees of freedom

Lukashov,

Simonov

2019

Preprint

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The Chiral Confining Lagrangian, based on the chiral theory with quark degrees of freedom, is used to study the spectroscopy of scalar mesons. The theory does not contain arbitrary fitting parameters and takes into account infinite number of transitions from meson-meson to quark-antiquark states. For chiral mesons the transition coefficients are known and the resulting ππ and K K amplitudes f ππ and f K K are calculated in terms of the q q and the free meson Green's functions. As a result the known q q pole at 1.05 GeV produces two resonances: a wide resonance E 1 in the range 500-700 MeV and narrow E 2 near 1 GeV, which can be associated with f 0 (500) and f 0 (980). A similar analysis, applied to the I = 1 channel, shows that in this case two very close poles in different sheets appear near E = 980 MeV, which can be associated with the a 0 (980) resonance. The resulting ππ interaction amplitudes, Re f ππ (E) and Im f ππ (E) are compared with the known data.

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“…. Estimated in the same way as in [28,35] for the 1P scalar state one has R ′ 1P (0) = 0.086 GeV 5/2 , ω 1 = ω 2 = 0.448 GeV [44] and according to (A1.6) one obtains (f…”

Section: Appendix A1 Decay Constants Of Scalar Mesonsmentioning

confidence: 95%

“…For the first excited state, 2P , one has for the scalar state ω(2P ) ∼ = 0.5 GeV, R ′ 2P (0) = 0.0817 GeV 5/2 , M(2P ) = 1.474 GeV [44].…”

Section: Appendix A1 Decay Constants Of Scalar Mesonsmentioning

confidence: 99%

Scalar mesons in the chiral theory with quark degrees of freedom

Lukashov,

Simonov

2019

Preprint

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Anti-NMDA receptor encephalitis

Azizova

Bembeeva

Kozyreva

et al. 2021

Nevrol. ž. im. L.O. Badalâna

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Autoimmune diseases of the central nervous system (CNS) are one of the most socially and economically significant problems of neurology. Despite the identification of new nosological forms of autoimmune encephalitis, the creation of diagnostic panels for the verification of autoantibodies in biological fluids, and the use of highly effective pathogenetic therapy, the number of diagnostic errors remains high, which poses a threat to the patient’s life and a high risk of developing severe complications. Anti-N-methyl-D-aspartate receptor encephalitis (anti-NMDAR encephalitis) is autoimmune encephalitis caused by the presence of antibodies (Ab) to the NR1 subunit of NMDA-receptors (NMDAR) characterized by the development of severe mental and neurological deficits in a previously healthy person. This article summarizes the recent literature on anti-NMDAR encephalitis. The literature search was carried out using the Scopus, Web of Science, Pubmed, CyberLeninka databases. The review presents the facts of the history of the study of the disease, epidemiological data, modern ideas about the pathogenetic mechanisms of the development of the disease, the spectrum of clinical manifestations and various forms of the course of the disease. The diagnostic criteria and research methods used to confirm the diagnosis are described, approaches to the treatment of anti-NMDAR encephalitis are outlined. Anti-NMDAR encephalitis is clinically manifested by a combination of mental disorders, epileptic seizures, speech and extrapyramidal disorders, and disturbances in the rhythm of sleep and wakefulness. The disease occurs at any age. The development of the disease can be associated with such immunological triggers as oncological process and herpetic encephalitis, or be idiopathic in nature. There are features of the course of the clinical picture depending on the age of the patient, paraneoplastic or postherpetic aetiology of the disease. The diagnostic algorithm, along with neuroimaging, determination of specific antibodies, electroencephalography, should also include the search for an oncological process. The recovery of patients can take from several months to years. In some cases, persistent neurological deficits develop. Predictors of a favourable outcome include early initiation and use of combination therapy, detection and removal of neoplasms, a low titer of anti-NMDAR antibodies, and age of patients over 12 years of age. In up to 25% of cases, a relapsing course of the disease is possible, and therefore requires long-term monitoring of these patients.

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Paradigms of modern epileptology

Abstract: The article is devoted to modern problems of epilepsy, discusses the perspectives on the etiology, pathogenesis, definition, epidemiology, modern classification, discusses the diagnosis and prediction of disease and treatment strategy.

Cited by 2 publications

References 199 publications

Scalar mesons in the chiral theory with quark degrees of freedom

Scalar mesons in the chiral theory with quark degrees of freedom

Anti-NMDA receptor encephalitis

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