Paradigm Shift in Ischemia Evaluation and Accumulating Evidence of Safety of Deferred Coronary Revascularization on the Basis of Invasive Fractional Flow Reserve Measurement

Abstract

servative strategy of medical therapy alone in stable CAD patients with moderate to severe ischemia, and reported no significant advantage of coronary revascularization over R ecently, the management of stable coronary artery disease (CAD) or chronic coronary syndrome has been hotly debated, including the diagnostic pathway of CAD and the role of coronary revascularization. The ISCHEMIA trial compared an invasive strategy (angiography and revascularization when feasible) with a con- Article p 1329The opinions expressed in this article are not necessarily those of the editors or of the Japanese Circulation Society.