Paracoccidioidomycosis

Restrepo, Ángela; Tobón, Ángela M.; Agudelo, Carlos A.

doi:10.1007/978-1-59745-325-7_18

Cited by 16 publications

(12 citation statements)

References 31 publications

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“…Otros hallazgos anormales son la elevación de las enzimas hepáticas, las bilirrubinas y la proteína C reactiva (PCR). En esta forma de presentación se conserva la función suprarrenal (10,11).…”

Section: Forma Aguda O Subaguda (Tipo Juvenil)unclassified

“…En más de 90 % de los casos, la visualización directa del hongo suele lograse con el examen en fresco con hidróxido de potasio (KOH) (11,22).…”

Section: Diagnósticounclassified

“…El cultivo debe realizarse en un medio adecuado, especialmente en agar de dextrosa Sabouraud o agar de extracto de levadura que contenga cloranfenicol y cicloheximida, en los cuales el hongo puede tardar de 20 a 30 días en crecer (11).…”

Section: Diagnósticounclassified

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Paracoccidioidomicosis juvenil diseminada diagnosticada en una niña en área urbana

et al. 2013

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Section: Forma Aguda O Subaguda (Tipo Juvenil)unclassified

“…En más de 90 % de los casos, la visualización directa del hongo suele lograse con el examen en fresco con hidróxido de potasio (KOH) (11,22).…”

Section: Diagnósticounclassified

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Paracoccidioidomicosis juvenil diseminada diagnosticada en una niña en área urbana

et al. 2013

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“…The prevalence is patients from 35 to 60 years of age, with predominance of male patients. In general, the disease appears to represent endogenous reactivation occurring years after initial contact with the fungus, as shown by diagnosed cases, United States, Europe, and Asia in patients who left endemicity countries many years earlier [11] [12] [24].…”

Section: Introductionmentioning

confidence: 99%

Ulcerated Lesion in Buccal Mucosa in a Patient with Paracoccidioidomycosis—Case Report

Vaz¹,

Pino²,

Costa³

et al. 2017

JBM

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Paracoccidioidomycosis is the most prevalent systemic mycosis in Latin America. It is a fungal infection caused by the dimorphic fungus Paracoccidioides brasiliensis. This microorganism can penetrate the human body through direct contact and can cause intense lymphadenopathy, ulcerated lesions in the oral cavity and in the skin among other alterations. In this study, we report a case of paracoccidioidomycosis with unusual clinical presentation, as it manifested in the female sex and although it did not present any relevant complaints of respiratory focus, it presented a single ulcerated lesion in the buccal mucosa. A biopsy of the lesion and a mycological examination revealed Paracoccidioides brasiliensis infection.

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“…1,2 Primary lung involvement leads to damage of multiple organs, including skin, mucous membranes, lymph nodes, adrenal glands, and central nervous system. 3 Adrenal insufficiency is a frequent complication of PCM; prevalence rates range from 2.9% to 48.2%, depending on the method used to diagnose the disorder. [4][5][6] The presence of P. brasiliensis in the adrenal gland has been reported, specifically in autopsy cases (85-90%), 6,7 and more recently, in patients who have been treated for the disease.…”

Section: Introductionmentioning

confidence: 99%

Adrenal Function Status in Patients with Paracoccidioidomycosis after Prolonged Post-Therapy Follow-Up

Tobón

Agudelo²,

Restrepo³

et al. 2010

The American Society of Tropical Medicine and Hygiene

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This study assessed adrenal function in patients with paracoccididioidomycosis who had been treated to determine a possible connection between high antibody titers and adrenal dysfunction attributable to persistence of the fungus in adrenal gland. Adrenal gland function was studied in 28 previously treated patients, 2 (7.1%) of whom were shown to have adrenal insufficiency and 7 (259%) who showed a below normal response to stimuli by adrenocorticotropic hormone. Paracoccidioides brasiliensis was detected in the adrenal gland from one of the patients with adrenal insufficiency. Although the study failed to demonstrate a significant difference between high antibody titers and low cortisol levels, the proportion of adrenal insufficiency detected and the subnormal response to adrenocorticotropic hormone confirmed that adrenal damage is an important sequela of paracoccidioidomycosis. Studies with a larger number of patients should be conducted to confirm the hypothesis of persistence of P. brasiliensis in adrenal gland after therapy.

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Paracoccidioidomycosis

Cited by 16 publications

References 31 publications

Paracoccidioidomicosis juvenil diseminada diagnosticada en una niña en área urbana

Paracoccidioidomicosis juvenil diseminada diagnosticada en una niña en área urbana

Ulcerated Lesion in Buccal Mucosa in a Patient with Paracoccidioidomycosis—Case Report

Adrenal Function Status in Patients with Paracoccidioidomycosis after Prolonged Post-Therapy Follow-Up

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