Paracoccidioidomicose Subaguda Septicêmica Levando a Infarto Esplênico E Trombose De Veia Porta No Indivíduo Imunocompetente: A Propósito De Um Caso

Disseminated juvenile paracoccidoidomycosis evolving with portal hypertension: a case report

“…The histopathological evaluation of the spleen, carried out in 2021, already suggested this complication. However, we emphasize that liver biopsy would be the gold standard test in case of diagnostic doubt 2,5 .…”

“…Six reports were identified in the medical literature, through a search in the databases of the Pubmed and Scielo platforms, with the following descriptors: "paracoccidioidomycosis" + "portal hypertension". Among these cases, we highlight that one individual was coinfected with schistosomiasis and the other with hepatitis C, diseases classically described as causes of portal hypertension 4,5 . Furthermore, hepatic involvement by PCM is also described in the medical literature as a consequence of perihepatic lymph node obstruction, inflammatory ductal fibrosis or even periampullary obstructive lesion, resulting in jaundice due to cholestatic syndrome 4,5,6,7,8,9,10 .…”

“…Among these cases, we highlight that one individual was coinfected with schistosomiasis and the other with hepatitis C, diseases classically described as causes of portal hypertension 4,5 . Furthermore, hepatic involvement by PCM is also described in the medical literature as a consequence of perihepatic lymph node obstruction, inflammatory ductal fibrosis or even periampullary obstructive lesion, resulting in jaundice due to cholestatic syndrome 4,5,6,7,8,9,10 . The rare cases that indicate this clinical manifestation highlight the importance of the differential diagnosis of PCM with proliferative diseases and periampullary tumors.…”