Parachordoma: a recurrent case and review of the literature

Abstract

Parachordoma is an uncommon tumor of soft tissue, and the origin is not clear. Recurrence and metastasis are rarely seen. A piecemeal mass measuring 7x4x3 cm was excised from a 28-year-man who had presented with pain and swelling of the right shoulder for 5 years. Histopathologically, the tumor was composed of cells with clear eosinophilic cytoplasm and an epithelioid appearance in a myxoid stroma separated by fibrous tissue with mild pleomorphism and mitotic activity. Tumoral cells were immunoreactive for cytokeratin 8/18, EMA, S-100 and vimentin, immunohistochemically. Recurrence was seen one year after the initial diagnosis. Areas of increased mitotic activity and atypical mitoses were observed in the recurrent tumor. We report this case as recurrence occurred earlier than usual and exhibited malignant features.

Recurrent metastasis of progressive parachordoma of spermatic duct to different sites in a year: A rare case

“…It is first reported by Laskowski in 1959 [4]. There is a slight male dominancy in parachordoma [4].…”

“…It is first reported by Laskowski in 1959 [4]. There is a slight male dominancy in parachordoma [4]. The average age is about 34.4 years [range 4-86 years old], however 20% of the patients are children in reported cases [2,5].…”

“…It is well circumscribed and pseudo capsulated with a thin fibrous tissue. It is usually 2-7 cm in size but can grove up to 12 cm [4]. Patient's first tumor size was 7 cm and second was 3 cm respectively.…”

“…It is curable with resection but sometimes recurrences and metastasis may occur from the tumor negative margins. Even its slow growth and locally invasive pattern, mortality with recurrence and metastasis in a year can be seen rarely [4]. There are only two deaths from metastatic parachordoma in the literature; however, some authors called parachordomas as low-grade sarcomas [7].…”

A case of parachordoma on the chest wall and literature review

“…The location in the 101-case series was distributed as the lower extremity in 41, upper extremity in 35, head and neck in 15 and the body in 10. [10] Parachordomas are usually painless tumors and are encountered as slow-growing masses. If it occur secondary changes or tumor compression, the patients will arise the signs of pain and body function limitation.…”