Paracetamol vs dexketoprofen for perineal pain relief after episiotomy or perineal tear

Abstract

A randomised controlled trial was conducted to investigate efficacy of paracetamol and dexketoprofen trometamol for perineal pain relief after perineal repair. Subjects were randomly assigned to receive two doses of either 50 mg of intravenous dexketoprofen trometamol via slow i.v. infusion (Group I, n = 49) or 1,000 mg of paracetamol via intravenous infusion (Group II, n = 46). The main outcome measure was a VAS (visual analogue scale) for pain recorded at 1 h (VAS 1). A total of 82 patients were included in the final analysis (Group I, n = 41; Group II, n = 41). There was no difference among groups in terms of pain scores at the beginning (VAS 0). The pain was decreased in 70% of the patients in Group I and in 62% of the patients in Group II (p = 0.502). Both paracetamol and dexketoprofen are effective in perineal pain relief after episiotomy or perineal tear repair.

Comparative evaluation of intravenous dexketoprofen and paracetamol in the management of pain induced by sore throat

“…Considering that pain decreased by 70% in the dexketoprofen group versus 62% in the paracetamol group (P = .502), both drugs were concluded to provide pain relief effectively following episiotomy and perineal repair, with no significant difference between them. 9 As in Akil et al's trial, dexketoprofen and paracetamol also provided pain relief equally in our study, with no significant clinical difference between them.…”

Do we need a core outcome set for childbirth perineal trauma research? A systematic review of outcome reporting in randomised trials evaluating the management of childbirth trauma

“…Forty‐eight randomised controlled trials, reporting data from 20 308 women, were included (Table S1). Seventeen interventions were evaluated, including different techniques (17 trials; 35%), different suture materials (six trials; 13%), and biofeedback (three studies; 6%). The majority of trials (71%) were published in general obstetrics and gynaecology journals.…”

Treatment of Patient Syndrome at the Ambulatory-Polyclinic Stage. Selection of the Analgetic From the Positions of Comorbidity and Drug Safety: In Focus Dexketoprofen

“…В течение длительного времени декскетопрофен успешно используется не только при стационарном, но и на амбулаторно-поликлиническом этапе лечения паци-ентов, в ортопедии и травматологии [34,37,38,47,48,55,[75][76][77], гинекологии [33,54,[78][79][80][81], общей хирургии [41,42,52,55,82,83], нейрохирургии [39,[84][85][86] и других отраслях медицины [5,56,60].…”