Paracetamol overdose secondary to dental pain: a case series

Siddique, Irfan; Mahmood, Hanya; Mohammed‐Ali, Ricardo

doi:10.1038/sj.bdj.2015.706

Cited by 18 publications

(17 citation statements)

References 10 publications

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“…Patients may not be aware of the paracetamol content of some over-the-counter analgesics and may combine them with generic paracetamol. Siddique et al 5 found that dental pain was the largest cause of accidental paracetamol overdose in a large case series. If more than 8 x 500 mg equivalent dose of paracetamol is found to have been taken…”

Section: Paracetamolmentioning

confidence: 98%

Safe use of paracetamol and high-dose NSAID analgesia in dentistry during the COVID-19 pandemic

et al. 2020

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Section: Paracetamolmentioning

confidence: 98%

Safe use of paracetamol and high-dose NSAID analgesia in dentistry during the COVID-19 pandemic

et al. 2020

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“…Moreover, orofacial pain is highly prevalent (Locker and Grushka 1987; Lipton et al 1993; Macfarlane et al 2002) and may reach high levels of intensity (Sharav et al 1984; Seymour et al 1985), similar to those observed in other painful diseases such as renal colic (>7/10 on a numerical rating scale) (Collaborative Group of the Spanish Society of Clinical Pharmacology 1991; Sasmaz and Kirpat 2019). This is further highlighted by the identification of dental pain as the major cause of acute medical admission due to unintentional paracetamol overdose (Siddique et al 2015; O’Sullivan et al 2018), which can lead to acute liver failure, a rare but potentially fatal adverse reaction. The high level and frequency of orofacial pain results in an elevated demand of emergency appointments in dental practice and in a certain proportion of general medical practices and emergency departments (Robertson et al 2015).…”

Section: Introductionmentioning

confidence: 99%

Dental Emergencies Management in COVID-19 Pandemic Peak: A Cohort Study

et al. 2021

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Due to the global coronavirus disease 2019 pandemic, the high risk of cross-contamination and the overload of hospital facilities have resulted in a real urgency for restricting dental emergency patient flow. In this context, the objectives of the current work were to 1) measure the ability of a triage-based management strategy to limit patient admission and 2) evaluate the success rate of both on-site and remote emergency management regarding symptom relief and pain control over a 1-mo period. We included all patients contacting the dental medicine department for an emergency consultation during the lockdown, between April 1 and April 30, 2020 ( N = 570). Following a telephone consultation and based on preestablished admission guidelines, a decision was made at baseline (T0) to either admit the patient for treatment or perform remote management by providing advice and/or drug prescription. Patients were then followed up systematically at 1 wk and 1 mo. Management failure was defined as the need for emergency admission for patients managed remotely since T0 and for new emergency admission for those admitted at T0. The global follow-up rate of patients with a complete data set was 91.4% ( N = 521). Of included patients, 49.3% could be managed without admission for emergency reasons for 1 mo. The proportion of successful management was 71.8% and 90.2% at 1 mo for remote and on-site management, respectively. To conclude, the proposed triage-based emergency management strategy with systematic follow-up was a good compromise between limiting patient admission and ensuring effective symptom relief and pain control. The strategy can be useful in situations where regulation of the emergency patient flow is required.

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“…Analgesics (particularly OTC drugs and non-opioids) are among the most frequently used medications globally (22,23). Despite the relatively low risk associated with most OTC over-the-counter analgesics, potential deleterious side effects can still be observed (26,37,38).…”

Section: Discussionmentioning

confidence: 99%

“…Several cases have been documented on analgesic overdose in patients frequenting a dental emergency service (25)(26)(27). In a study, the main cause of the visit (66%) to a dental emergency service was a pain, whereby an overwhelming majority (89%) had been experiencing pain for over a week prior to seeking treatment (28).…”

Section: Introductionmentioning

confidence: 99%

Prevalence of Self-Medication with Analgesics Among People Referring to Outpatient Dental Clinics in an Iranian Population

Mohammadi

Dehghani

Emad

et al. 2019

Int J High Risk Behav Addict

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Background: Self-medication is a behavior in which a person, without the use of professional advice, resolves his health problem. Self-medication is common in the world and considered as a growing public health problem. Objectives:The aim of the present study was to determine the prevalence of self-medication with analgesics for dental problems over a two-year period among a population in Shiraz, Iran. Patients and Methods: This cross-sectional study recruited 1,203 people. They were randomly selected from among men and women older than 12 with a mean age of 36.2 years, attending outpatient health clinics in 10 districts of Shiraz. A researcher-made questionnaire was used to collect data on demographic variables, dental pain, and self-care remedies utilized to combat dental pain. SPSS version 22 software was used for statistical analysis by the chi-square test and one-way ANOVA. The values of P < 0.05 were considered significant. Results: The prevalence of self-medication was 56.1% and the most common reasons for self-medication were having severe pain (35.3%), having prior experience (15.9%), and the high cost of dental visits (13.5%). The most common self-used drugs were Ibuprofen (29.42%) and Acetaminophen (21.61%). Self-medication was not significantly related to variables such as educational level, gender, and marital status and was related to age and salary. Conclusions: As found in our study, the high prevalence of self-medication is a major concern. There is a need for health education on indications and risks of self-medication.

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Paracetamol overdose secondary to dental pain: a case series

Abstract: Dental pain is the single most common cause of acute medical admission secondary to unintentional paracetamol overdose. Patients registered with a general dental practitioner (GDP), as well as those not registered with a GDP, had difficulty accessing timely emergency primary dental care.

Cited by 18 publications

References 10 publications

Safe use of paracetamol and high-dose NSAID analgesia in dentistry during the COVID-19 pandemic

Safe use of paracetamol and high-dose NSAID analgesia in dentistry during the COVID-19 pandemic

Dental Emergencies Management in COVID-19 Pandemic Peak: A Cohort Study

Prevalence of Self-Medication with Analgesics Among People Referring to Outpatient Dental Clinics in an Iranian Population

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