Paracentral Acute Middle Maculopathy as the Presenting Manifestation of Giant Cell Arteritis

Pellegrini, F.; Brocca, Daniele; Calandriello, L.; Cuna, Alessandra; Leonardi, Francesca; Lee, Andrew G

doi:10.1097/wno.0000000000001483

Cited by 5 publications

(4 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Section: Etiologies Of Paracentral Acute Middle Maculopathymentioning

confidence: 99%

“…Recent reports suggest that PAMM may be the only ocular sign leading to the diagnosis of giant cell arteritis (GCA) or carotid occlusive disease and so detection of this OCT finding can be critical especially when isolated. [24][25][26] Paracentral Acute Middle Maculopathy as a Sign of Giant Cell Arteritis Serum erythrocyte sedimentation rate was urgently acquired and was elevated (63 mm/hour. Normal , 20 mm/hour).…”

Section: Etiologies Of Paracentral Acute Middle Maculopathymentioning

confidence: 99%

“…The most common etiologies of vision loss in GCA are arteritic anterior ischemic optic neuropathy (A-AION) and occlusion of the central retinal artery or cilioretinal artery. Recently, several cases of PAMM have been described as a primary manifestation of GCA 24 or in association with AION or cotton wool spots. 27 In a retrospective study including 96 patients with GCA, Mairot et al 25 reported ocular involvement in 52 cases (54.2%).…”

Section: Etiologies Of Paracentral Acute Middle Maculopathymentioning

confidence: 99%

See 2 more Smart Citations

Detection of Paracentral Acute Middle Maculopathy Can Prevent Blindness and Death

Bousquet,

Santina,

Abraham

et al. 2023

Retina

View full text Add to dashboard Cite

Depth resolved imaging tools such as optical coherence tomography (OCT) are at the forefront of a new era of retinal diagnostics. These advancements have remarkably broadened our understanding of macular ischemia and the structure of the retinal capillary plexus (RCP). Because of the predominant vertical organization of the RCP, the middle retinal layer is at greater risk of ischemia and infarction. Paracentral acute middle maculopathy (PAMM) is a manifestation of this risk and is the result of infarction of the inner nuclear layer (INL), detectable on OCT as a hyperreflective band within the INL. On OCT angiography (OCTA), PAMM is the result of hypoperfusion of the deep retinal vascular complex i.e the intermediate retinal capillary plexus and the deep retinal capillary plexus.

show abstract

Section: Etiologies Of Paracentral Acute Middle Maculopathymentioning

confidence: 99%

Section: Etiologies Of Paracentral Acute Middle Maculopathymentioning

confidence: 99%

Section: Etiologies Of Paracentral Acute Middle Maculopathymentioning

confidence: 99%

See 1 more Smart Citation

Detection of Paracentral Acute Middle Maculopathy Can Prevent Blindness and Death

Bousquet,

Santina,

Abraham

et al. 2023

Retina

View full text Add to dashboard Cite

show abstract

“…1 Although the visual loss in GCA is typically the result of involvement of the optic nerve (e.g., anterior ischemic optic neuropathy [AION] and posterior ischemic optic neuropathy [PION]) or the central retinal artery, 2 recent cases of paracentral acute middle maculopathy (PAMM) have been described in GCA. 3 We describe a representative case and summarize the literature on PAMM in GCA.…”

mentioning

confidence: 99%

Paracentral Acute Middle Maculopathy in Giant Cell Arteritis

Pellegrini

Mairot

Cuna³

et al. 2024

RETINAL Cases &Amp; Brief Reports

Self Cite

View full text Add to dashboard Cite

Purpose: To describe a representative case and review the literature on paracentral acute middle maculopathy (PAMM) and giant cell arteritis (GCA).Methods: A review of the English-language ophthalmic literature was performed using the search terms of PAMM, giant cell arteritis, and temporal arteritis.Results: A 72-year-old woman with PAMM as the presenting ophthalmic manifestation of GCA was described with a review of the prior cases from the literature. It was found that there were 26 cases of PAMM in GCA. In 19 of 26 cases, PAMM was associated with no other fundus abnormalities and was only seen on multimodal imaging including optical coherence tomography.Conclusion: PAMM can cause acute paracentral visual loss, and GCA should be suspected in all cases of PAMM of the elderly patients, even when isolated and not associated with constitutional symptoms of GCA.

show abstract