Para-testicular florid cystic müllerianosis in an elderly patient: Case report of a rare metaplastic change of tunica vaginalis with unusual clinical presentation (mass forming lesion)

Mullerian Serous Cystadenoma Occurring in the Scrotum Post-Orchidopexy: A Rarely Reported Yet Distinctive Entity

“…6 It is likely that previous reports of Mullerian metaplasia and "florid cystic Mullerianosis" of the tunica vaginalis represent a precursor lesion in the same spectrum of disease as serous cystadenoma due to similar histologic and immunohistochemical features. 7,8 In a series of 146 para-testicular epithelial tumors, serous cystadenomas were found to comprise 6 cases (4%) and Mullerian cysts a further 2 cases (1%). 9 The etiology of serous cystadenoma is unknown.…”

“…1,12 Serous cystadenoma and florid cystic Mullerianosis have been known to pose a clinical and radiological diagnostic challenge, including mimicking testicular malignancy in adult patients, with previous reports arising from the epididymis, tunica albuginea, and tunica vaginalis. 8,12,13 There is limited data on the prognosis and no consensus guidelines for treatment. No recurrence has been reported after total resection, which has typically been by orchidectomy in previous reports.…”

“…No recurrence has been reported after total resection, which has typically been by orchidectomy in previous reports. 1,8,12,13 However, some cases of epididymal serous cystadenoma have been treated with simple cystectomy and have shown no recurrence. 14,15 A case of scrotal serous cystadenoma occurring at the site of prior orchidopexy has been previously reported and is strikingly similar to our case.…”

“…No recurrence has been reported after total resection, which has typically been by orchidectomy in previous reports. 1,8,12,13 However, some cases of epididymal serous cystadenoma have been treated with simple cystectomy and have shown no recurrence. 14,15…”