Papular-Purpuric Gloves and Socks Syndrome in Children and Adolescents

Fretzayas, Andrew; Douros, Konstantinos; Moustaki, Maria; Nicolaidou, Polyxeni

doi:10.1097/inf.0b013e31818cb289

Cited by 36 publications

(30 citation statements)

References 18 publications

(4 reference statements)

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“…31 A petechial and purpuric rash was documented in 17% of our patients, most often in those aged .5 years and most frequently found on acral sites. Petechial and purpuric eruptions are a known cutaneous manifestation of enteroviral infections, 32,33 and CVA6 infection should be added to the differential diagnosis of acral purpura, particularly in the setting of a community outbreak.…”

Section: Figurementioning

confidence: 99%

“Eczema Coxsackium” and Unusual Cutaneous Findings in an Enterovirus Outbreak

Oza²,

et al. 2013

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OBJECTIVE: To characterize the atypical cutaneous presentations in the coxsackievirus A6 (CVA6)–associated North American enterovirus outbreak of 2011–2012. METHODS: We performed a retrospective case series of pediatric patients who presented with atypical cases of hand, foot, and mouth disease (HFMD) from July 2011 to June 2012 at 7 academic pediatric dermatology centers. Patients were included if they tested positive for CVA6 or if they met clinical criteria for atypical HFMD (an enanthem or exanthem characteristic of HFMD with unusual morphology or extent of cutaneous findings). We collected demographic, epidemiologic, and clinical data including history of skin conditions, morphology and extent of exanthem, systemic symptoms, and diagnostic test results. RESULTS: Eighty patients were included in this study (median age 1.5 years, range 4 months–16 years). Seventeen patients were CVA6-positive, and 63 met clinical inclusion criteria. Ninety-nine percent of patients exhibited a vesiculobullous and erosive eruption; 61% of patients had rash involving >10% body surface area. The exanthem had a perioral, extremity, and truncal distribution in addition to involving classic HFMD areas such as palms, soles, and buttocks. In 55% of patients, the eruption was accentuated in areas of eczematous dermatitis, termed “eczema coxsackium.” Other morphologies included Gianotti-Crosti–like (37%), petechial/purpuric (17%) eruptions, and delayed onychomadesis and palm and sole desquamation. There were no patients with serious systemic complications. CONCLUSIONS: The CVA6-associated enterovirus outbreak was responsible for an exanthem potentially more widespread, severe, and varied than classic HFMD that could be confused with bullous impetigo, eczema herpeticum, vasculitis, and primary immunobullous disease.

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Section: Figurementioning

confidence: 99%

“Eczema Coxsackium” and Unusual Cutaneous Findings in an Enterovirus Outbreak

Oza²,

et al. 2013

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“…3,34 PPGSS has mainly been described in young adults. 3,38,39 To date, more than 70 cases have been documented in the literature. 34 PVB19 has been implicated as the major causative agent of the syndrome; however, other viruses have been also defined as etiologic agent for this disease.…”

Section: Accepted Manuscriptmentioning

confidence: 98%

“…[34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50] Papular-purpuric gloves and socks syndrome is an acute self limiting pruritic dermatosis that affects the distal extremities in a gloves and socks pattern. PPGSS presents initially with erythema and popular oedema and may also be associated purpura and rarely petechiae.…”

Section: Accepted Manuscriptmentioning

confidence: 99%

Viral infections of the folds (intertriginous areas)

Adışen

Önder

2015

Clinics in Dermatology

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“…Иногда острая инфекция приводит к пневмонии, мононуклеозоподобному синдрому, миокардиту, тромбоцитопенической пурпуре, розео-лезно-папулезной экзантеме по типу «перчаток и но-сков», папулезному акродерматиту (синдром Джа-нотти-Крости), пурпуре [43][44][45][46][47]. У детей раннего возраста, перенесших ВГЧ6-инфекцию, регистриро-вали развитие синдрома Гийена-Барре [48], пораже-ние лицевого нерва [49].…”

Section: российский вестник перинатологии и педиатрии 2016; 61:5 Rosunclassified

Infections caused by herpes virus type 6: modern features

Анохин¹,

Sabitova²

2016

Ross. vestn. perinatol. pediatr.

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Papular-Purpuric Gloves and Socks Syndrome in Children and Adolescents

Cited by 36 publications

References 18 publications

“Eczema Coxsackium” and Unusual Cutaneous Findings in an Enterovirus Outbreak

“Eczema Coxsackium” and Unusual Cutaneous Findings in an Enterovirus Outbreak

Viral infections of the folds (intertriginous areas)

Infections caused by herpes virus type 6: modern features

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