Papular Mycosis Fungoides on the Legs: A Case Report

Painful Palmoplantar Lesions Following Vaccination: Answer

“…4 Papular mycosis fungoides is the early stage of MF, and it is defined by small, persistent, red to brown, nonfollicular papules with symmetrical involvement. 5 Biopsy reveals a perivascular to band-like infiltrate located in the papillary dermis of scattered atypical lymphocytes with a cerebriform nuclei and a variable degree of epidermotropism. When lesions progress, the dermal infiltrate increases and Pautrier abscess can be observed.…”

“…Immunochemistry generally shows an aberrant T-helper phenotype, CD4-positive, and CD7/30negative, unless transformation into a high-grade large-cell lymphoma occurs. 4,5 MS is an infrequent variant of secondary syphilis characterized by an ulcerative necrotic papulonodular rash. It principally affects immunocompromised patients, albeit cases in immunocompetent individuals have also been published.…”

“…Immunochemistry generally shows an aberrant T-helper phenotype, CD4-positive, and CD7/30-negative, unless transformation into a high-grade large-cell lymphoma occurs. 4,5…”

Commentary about papular mycosis fungoides, lymphomatoid papulosis and lymphomatoid pityriasis lichenoides: more similarities than differences

“…Since Kodama et al's report, there have been 10 additional cases of papular MF published in the literature . Together these cases (eight men, eight women) had persistent papules, sometimes only a few millimeters in diameter, that did not enlarge into nodules, plaques or tumors.…”