Papillomaviruses: HPV as the etiological factor of head and neck cancers

Background: Today, human papillomavirus (HPV) infection has become the most common sexually transmitted disease worldwide. Major consequences of contracting the virus include both mild skin lesions and a range of cancers, the most frequent of which are cervical cancer, penile cancer, oral cavity cancer, throat cancer, and anal cancer, undoubtedly demonstrating its high oncogenic potential. Aim of the study: The objective of this study is to determine the level of knowledge among men aged 18–26 years with regard to HPV prevention and treatment. Materials and methods: An online survey was conducted using a questionnaire developed by the authors. The questionnaire was comprised of 16 closed-ended questions and 5 questions pertaining to demographics. Chi-squared tests or Spearman’s rank correlation coefficients were used for the statistical analysis. Results: Only 27.5% of the respondents correctly answered a question regarding the number of types of the virus, and 33% correctly determined the percentage of the cases where an active infection turns into a chronic state. However, a high level of awareness of the routes of infection was demonstrated, with more than half of the respondents (63%) answering this question correctly. Additionally, more than two-thirds (67.9%) of the men indicated correctly that one of the factors facilitating infection is a young age at the time of the first contact with the virus. Nearly all respondents (90%) indicated that using condoms is an effective form of prevention. Conclusions: The results expressly indicate an insufficient level of knowledge regarding HPV among young men. Due to the high level of sexual activity in this age group, increased education with regard to the prevention of sexually transmitted diseases is needed.

show abstract

Knowledge of prevention and treatment of human papillomavirus (HPV) infections among young men

Florkiewicz

Tobolska

Bączek

2021

MSP

View full text Add to dashboard Cite

show abstract

The role of HPV CMV and EBV latent viruses of the development of Oropharyngeal squamous cell carcinoma (OPSCC)

et al. 2022

View full text Add to dashboard Cite

Background: In recent years, a dynamic increase in the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has been observed, especially in highly developed countries. As in the case of anal and genital cancers, a significant proportion of OPSCC (about 60%) is due to sexually acquired HPV infection, and the increase in OPSCC is attributed to changes in sexual behavior in Western countries. EBV and CMV viruses are also characterized by carcinogenesis, but the literature data on their participation in the development of neoplasms of the middle throat are still very limited. Objective: The aim of this article is to review the latest scientific reports on the impact of infections with latent viruses (HPV, EBV, CMV) on the oncogenesis process in the middle pharynx and to summarize the prophylactic options using the available multivalent vaccines against HPV infections. Conclusions: HPV-positive oropharyngeal squamous cell carcinoma of the middle pharynx is a significant clinical problem due to the increase in the number of cases, especially in young people, who lack classic risk factors, such as exposure to tobacco and alcohol. HPV-dependent neoplasms are characterized by a better prognosis and less invasive oncological therapy (radiotherapy and chemotherapy). Of central importance in the prevention of HPV-positive OPSCC in both women and men is prophylaxis with multivalent vaccination. Due to the lack of sufficient data on the participation of EBV and CMV viruses in the development of OPSCC, as well as the lack of prophylaxis, intensive research in this area is necessary.

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

334 Leonard St

Brooklyn, NY 11211

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Papillomaviruses: HPV as the etiological factor of head and neck cancers

Cited by 2 publications

References 45 publications

Knowledge of prevention and treatment of human papillomavirus (HPV) infections among young men

Knowledge of prevention and treatment of human papillomavirus (HPV) infections among young men

The role of HPV CMV and EBV latent viruses of the development of Oropharyngeal squamous cell carcinoma (OPSCC)

Contact Info

Product

Resources

About