Papillary Thyroid Carcinoma with an Uncommon Spread of Hematogenous Metastases to the Choroid and the Skin

Bucerius, Jan; Meyka, Susanne; Bangard, M.; Biersack, Hans‐Jürgen; Eter, Nicole

doi:10.1016/s0027-9684(15)31183-4

Cited by 21 publications

(15 citation statements)

References 8 publications

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“…In a study of 420 patients with uveal metastasis, thyroid cancer was demonstrated in 2 cases [8]. Two other studies also found 15 cases of metastatic thyroid carcinoma to the eye, follicular thyroid carcinomas being the most common cause [9,10]. Clinically, patients generally present with symptoms of pain and impairment of vision.…”

Section: Discussionmentioning

confidence: 99%

Iodophilic Synchronous Phalangeal and Choroidal Metastasis from Follicular Thyroid Carcinoma: A Case Report and Review

Patil¹,

Kattepur²,

Gopinath³

et al. 2014

Eur Thyroid J

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Background: Follicular thyroid cancers constitute 15-20% of all thyroid tumors. The usual mode of dissemination is via the hematogenous route. The most common sites of distant metastasis are to the lungs and bones. Objective: A case is presented to demonstrate the unusual presentation of follicular cancer with synchronous digital (distal phalanx of the little finger) and choroidal metastasis that was responsive to radioiodine treatment. Case Report: A 54-year-old female presented with swelling over the terminal part of the left little finger with thyromegaly. Investigations revealed metastasis from follicular thyroid cancer to the little finger along with pulmonary metastases. She underwent total thyroidectomy with central compartment clearance followed by ¹³¹I therapy. Subsequent follow-up demonstrated complete regression of the digital metastasis and partial regression of the choroidal metastasis which was evaluated after the radioiodine scan that picked up the choroidal metastasis. Conclusion: Follicular thyroid cancers can rarely spread to unusual sites like the digits and choroid. This report highlights the synchronous presentation of digital and choroidal metastasis which responded to ¹³¹I therapy.

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Section: Discussionmentioning

confidence: 99%

Iodophilic Synchronous Phalangeal and Choroidal Metastasis from Follicular Thyroid Carcinoma: A Case Report and Review

Patil¹,

Kattepur²,

Gopinath³

et al. 2014

Eur Thyroid J

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“…5 Both simultaneous choroid and skin involvement have also been seen. 1,3,4 Uveal metastases in general are not infrequently reported. A large, retrospective single center review of 520 eyes (420 patients) with uveal metastases over a 20-year period reported that the commonest primary sites were breast (47c), lung (21%), gastrointestinal tract (4%), kidney (2%), skin (2%) and prostate (2%).…”

Section: Discussionmentioning

confidence: 99%

“…This is most likely due to its reduced rate of hematogenous spread (14%) as compared to the rate of local node invasion (42%). [1][2][3] If PTC metastasises, it typically goes to lung, bone and brain, with uveal metastases being distinctly rare, with six previous reports. [1][2][3][4][5] Bilateral choroidal PTC metastases have been only reported twice.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3] If PTC metastasises, it typically goes to lung, bone and brain, with uveal metastases being distinctly rare, with six previous reports. [1][2][3][4][5] Bilateral choroidal PTC metastases have been only reported twice. 1,4 We report another case that presented with ocular symptoms within 12 months of her initial diagnosis in the context of widespread disseminated disease.…”

Section: Introductionmentioning

confidence: 99%

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Clinicopathological report: Bilateral choroidal metastases from papillary thyroid cancer

Tran

Bigby

Hughes

et al. 2010

Asia-Pac J Clncl Oncology

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Bilateral uveal metastases from papillary thyroid carcinoma are extremely rare. A 36-year-old woman with a 12-month history of papillary thyroid carcinoma presented with sudden loss of visual acuity and fields in the left eye. An examination and B-scan revealed a large, solid choroidal lesion in the left eye causing exudative retinal detachment. A small solid mass was also observed in the right eye fundus. Following left eye enucleation, immunohistopathology confirmed metastatic papillary thyroid carcinoma. The authors report the third known case of bilateral choroidal metastases.

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“…Em números absolutos, o tumor de mama aparece como o tumor primário responsável pela maior parte das metástases oculares (28,6%) (9) . Outros tumores associados à metástase ocular são gastrointestinais, renais, dermatológicos, urogenitais, tireoideanos, de glândula salivar e processos leucêmicos (1,9,11,(14)(15)(16)(17)(18) .…”

Section: Quadro Clínicounclassified

Tumor metastático uveal: revisão de literatura sobre a neoplasia ocular maligna mais comum

Meyer¹

2011

Rev. bras.oftalmol.

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Papillary Thyroid Carcinoma with an Uncommon Spread of Hematogenous Metastases to the Choroid and the Skin

Cited by 21 publications

References 8 publications

Iodophilic Synchronous Phalangeal and Choroidal Metastasis from Follicular Thyroid Carcinoma: A Case Report and Review

Iodophilic Synchronous Phalangeal and Choroidal Metastasis from Follicular Thyroid Carcinoma: A Case Report and Review

Clinicopathological report: Bilateral choroidal metastases from papillary thyroid cancer

Tumor metastático uveal: revisão de literatura sobre a neoplasia ocular maligna mais comum

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