Papillary Thyroid Cancer Remodels the Genomic Fabrics of DNA Replication, Repair and Transcription
Dumitru A Iacobas,
Sanda Iacobas
Abstract:The genetic causes of the differentiated, highly treatable and mostly non-fatal papillary thyroid cancer (PTC) are not yet fully known. The widely accepted PTC etiology blames altered sequence or/and expression level of certain biomarker genes. However, our previous studies found that the PTC biomarkers played significantly lower roles than the personalized PTC Gene Master Regulators. Our publicly accessible gene expression data from the cancer nodule and the surrounding normal tissue of surgically removed PTC… Show more
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