Papillary cystic neoplasm of the pancreas: Radiological findings

Procacci, Carlo; Graziani, Rossella; Bicego, E.; Zicari, Marianna; Andreis, I. A. Bergamo; Zamboni, Giuseppe; Iacono, Calogero; Mainardi, Paride; Valdo, Moreno; Pistolesi, G. F.

doi:10.1007/bf01256710

Cited by 31 publications

(16 citation statements)

References 14 publications

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“…6,7 The tumors are usually round to ovoid and solitary Calcifications are occasionally seen most commonly in the capsule. 8,9 In our case, the tumor was small and solid, with little degeneration such as hemorrhage and calcification, which was not typical for SPT.…”

Section: Discussionmentioning

confidence: 99%

F-18 Fluorodeoxyglucose Uptake in a Solid Pseudopapillary Tumor of the Pancreas Mimicking Malignancy

Shimada

Nakamoto²,

Isoda³

et al. 2008

Clinical Nuclear Medicine

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Solid pseudopapillary tumors (SPTs), predominantly affecting young women, are rare pancreatic tumors. It is reported that imaging features of SPT are solid and cystic components, and there is intratumoral hemorrhage and calcification. However, findings of positron emission tomography (PET) using F-18 fluorodeoxyglucose (FDG) with pathologic correlation have not been fully evaluated. We present a case of SPT that mimicked malignancy on FDG-PET.

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Section: Discussionmentioning

confidence: 99%

F-18 Fluorodeoxyglucose Uptake in a Solid Pseudopapillary Tumor of the Pancreas Mimicking Malignancy

Shimada

Nakamoto²,

Isoda³

et al. 2008

Clinical Nuclear Medicine

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“…CT scan has a good sensitivity rate in detecting these tumors [6]. The presence of an SPN is highly suggested when certain pathognomonic features are identified on CT scan [7]: well-defined, encapsulated mass with areas of central calcification, necrosis or hemorrhage.…”

Section: Discussionmentioning

confidence: 99%

Solid Pseudopapillary Tumor of the Pancreas: An Unusual Cause of Abdominal Pain

Kesavan

et al. 2017

Cureus

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Solid-pseudopapillary neoplasm (SPN) of the pancreas is a rare tumor that accounts for less than one percent of pancreatic tumors. The diagnosis could be challenging as SPN tend to manifest with nonspecific abdominal symptoms, variable radiological features, and inconsistent morphology. The cellular origin of SPN is unclear and might involve ductal, acinar and endocrine stem cells. We report a rare case of a 27-year-old female who presented with intermittent abdominal pain for two years, associated with a decrease in appetite. Her medical history was significant for abdominoplasty five years ago. Vital signs were stable. Physical examination revealed mild epigastric tenderness. Laboratory tests were unremarkable. Contrast computed tomography (CT) scan of the abdomen showed a 2 x 2 cm indeterminate pancreatic tail lesion. An endoscopic ultrasound (EUS) disclosed a 2.1 x 1.8 cm hypoechoic mass in the tail of the pancreas.Trans-gastric fine needle aspiration was obtained to show clusters of uniform neoplastic cells with abundant cytoplasm and oval bean-shaped nuclei. Immunohistochemical stains were positive for beta-catenin, Vimentin, CD10, CD56, cytokeratin-7 (Ck7), Cyclin D1, and negative for chromogranin, epithelial-cadherin (E cadherin) which was consistent with a pseudopapillary tumor. The patient underwent a robotic assisted en-bloc distal pancreatectomy and splenectomy. There were no intra-abdominal metastases.SPN is a rare tumor characterized by a specific immunohistological pattern which makes it highly distinct from other pancreatic neoplasms particularly neuroendocrine tumors, acinar carcinomas, and carcinoids. It is important to differentiate SPN from other pancreatic neoplasms because it is characterized as low potential for malignancy and a favorable prognosis after resection, with a five-year survival rate approaching 85%-95%.

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“…In fact, the enlarged spleen can mimic a tumor arising from the neighboring organ, depending on the site of occurrence. Among abdominal tumors, considering the site, it is not irrational to think that, when a markedly enlarged spleen extends to the right upper abdomen and compresses the pancreas backward, it may mimic a huge cystic tumor of the pancreas, such as a papillary cystic neoplasm of the pancreas [10].…”

Section: Discussionmentioning

confidence: 99%

Splenic lymphangioma: US and CT diagnosis and clinical manifestations

et al. 1999

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(1) When US shows multiple cysts of different sizes in the spleen, the diagnosis of splenic lymphangioma is not difficult to make with US and CT alone. (2) Color Doppler sonography is a very useful tool to increase diagnostic confidence because it demonstrates the vasculature of the mass. (3) When examining patients with splenic lymphangioma, one should consider the possibility of multiorgan involvement.

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Papillary cystic neoplasm of the pancreas: Radiological findings

Cited by 31 publications

References 14 publications

F-18 Fluorodeoxyglucose Uptake in a Solid Pseudopapillary Tumor of the Pancreas Mimicking Malignancy

F-18 Fluorodeoxyglucose Uptake in a Solid Pseudopapillary Tumor of the Pancreas Mimicking Malignancy

Solid Pseudopapillary Tumor of the Pancreas: An Unusual Cause of Abdominal Pain

Splenic lymphangioma: US and CT diagnosis and clinical manifestations

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