Papillary cystadenocarcinoma of submandibular salivary gland: A rare case report

Mardi, Kavita; Sharma, Sudarshan; Gupta, Neelam

doi:10.4103/0973-1482.73346

Cited by 12 publications

(9 citation statements)

References 10 publications

(12 reference statements)

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“…24 Stromal fragments may also be seen in the form of hyaline globules. 35 Hyaline globules were absent in both the epithelial sheets and cores of the papillae in Papillary cystadenoma.…”

Section: Discussionmentioning

confidence: 96%

Diagnostic discrepancies in fine needle aspiration diagnosis of parotid gland lesions in a resource limited hilly region

2020

IJPO

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The characteristic cytological features of parotid gland lesions have been well described in literatures, but there also exist cytological diagnostic pitfalls that make it difficult to form an accurate diagnosis in some cases. Aim: To evaluate the sensitivity, specificity, along with positive predictive value, negative predictive value by Cyto-histological correlation in various lesions with an emphasis on discordant cases. Materials and Methods: A retro-prospective study of 250 non-guided/palpable FNAC of suspected parotid gland enlargements were performed from 2006 to 2018 at tertiary care hospital. The cytological smears were stained with May grunwald giemsa, papanicolaou, hematoxylin eosin stains. Surgically resected specimens were received for histopathology in 103 relevant cases only. The cytologic and Histologic slides were studied, compared and correlated where ever possible and statistical analysis done. Result: Out of 250 patients male to female ratio was 1.4: 1. The different categories of salivary gland lesions included: non neoplastic, benign and malignant constituted 109,108 and 33 cases respectively. Pleomorphic adenoma and mucoepidermoid carcinoma was the commonest benign and malignant neoplasm reported in this study respectively. False negative and false positive results were mainly due to cystic and papillary lesions. The sensitivity, specificity, along with positive predictive value, negative predictive value and diagnostic accuracy of present study was 68.42%, 98.80%, 92.85%, 93.25% and93.20% respectively. Conclusion: Though palpable FNAC of the parotid gland tumors is simple, rapid and cost-effective in a developing country but rate of characterization of specific type of parotid gland tumor is lower due to overlapping cytomorphology.

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“…24 Stromal fragments may also be seen in the form of hyaline globules. 35 Hyaline globules were absent in both the epithelial sheets and cores of the papillae in Papillary cystadenoma.…”

Section: Discussionmentioning

confidence: 96%

Diagnostic discrepancies in fine needle aspiration diagnosis of parotid gland lesions in a resource limited hilly region

2020

IJPO

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“…It is conceptually the malignant counterpart of benign cystadenoma and the histological diagnosis rests on actual infiltration of surrounding parenchyma and underlying connective tissue. [ 1 ] There are a few reports describing its cytological features.…”

Section: Discussionmentioning

confidence: 99%

“…Major locations in decreasing order of frequency include minor salivary gland, parotid gland, and submandibular gland. [ 1 ] It accounts for 2% of all malignant salivary gland tumors. [ 2 ] The cytological features can overlap with various benign and malignant neoplasms having papillary pattern.…”

Section: Introductionmentioning

confidence: 99%

Cytomorphological features of papillary cystadenocarcinoma of parotid gland: A case report with review of literature

et al. 2016

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Papillary cystadenocarcinoma is a very rare slow growing malignant neoplasm characterized by cysts and intraluminal papillary projections. It is defined by WHO as a separate entity. On FNA, cytological features can mimic with various papillary and cystic neoplasms of salivary gland. It is also difficult to distinguish from benign salivary gland neoplasms as it has bland nuclear features. Thus we present cytomorphological features and discuss its differential diagnosis with neoplasms having prominent papillary architecture with review of literature.

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“…67 Many cell types can be observed in CAC including small cuboidal (constituting the majority of the neoplastic cells), tall cuboidal, tall columnar, mucinous, finely vacuolated (soap-bubble like appearance), clear, oncocytic and rarely, focal epidermoid cells. 60,64,[68][69][70][71] Osseous metaplasia has also been observed in CAC. 72 Finally, it is worth mentioning that CAC can only be differentiated form cystadenoma histologically, by demonstrating an infiltrative growth into adjacent salivary gland tissue.…”

Section: General Featuresmentioning

confidence: 99%

Cytopathology approach to rare salivary gland lesions with oncocytic features

Hussein

Khader

2019

Diagnostic Cytopathology

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Salivary glands located in the head and neck area are known to have different lesions with prominent oncocytic features. Fine needle aspiration is usually the initial approach in the management of these lesions, whether they represent neoplastic or non‐neoplastic processes. Owing to the limited material present upon cytopathologic examination, knowledge of variants and subtypes of various oncocytic lesions that can occur in this area is of major importance to provide the most accurate interpretation to the patients and clinicians. In this article, we selected rare lesions of the salivary glands that may exhibit oncocytic changes, and provided a brief discussion of each one of them, with emphasis on challenges in navigating the differential diagnosis that these cases may pose, from the cytopathology standpoint.

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Papillary cystadenocarcinoma of submandibular salivary gland: A rare case report

Cited by 12 publications

References 10 publications

Diagnostic discrepancies in fine needle aspiration diagnosis of parotid gland lesions in a resource limited hilly region

Diagnostic discrepancies in fine needle aspiration diagnosis of parotid gland lesions in a resource limited hilly region

Cytomorphological features of papillary cystadenocarcinoma of parotid gland: A case report with review of literature

Cytopathology approach to rare salivary gland lesions with oncocytic features

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