Papillary Carcinoma Thyroid in a Thyroglossal Cyst

Chauhan, Ashutosh; Kakkar, Sunita; Gupta, Aakriti

doi:10.1016/s0377-1237(09)80069-5

Cited by 3 publications

(3 citation statements)

References 15 publications

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“…[14] Papillary carcinoma is the most common malignancy found in a thyroglossal duct cyst (80%), followed by follicular or mixed papillary-follicular carcinoma (9%), squamous cell carcinoma (5%), adenocarcinoma (2%), anaplastic carcinoma (1%) and others (3%). [15] The prognosis of papillary carcinoma arising in thyroglossal duct cyst is good and has an overall survival rate of 95.6% at 10 years. [16] According to the Widstrom et al criteria, the diagnosis of primary carcinoma of the thyroglossal duct includes the histological identification of thyroglossal duct carcinoma, demonstration of the normal epithelial lining of the thyroglossal duct, normal thyroid follicles within walls of the cyst, normal thyroid tissue adjacent to the tumour and no findings of primary thyroid carcinoma on histopathological examination of the thyroid gland.…”

Section: Discussionmentioning

confidence: 99%

Papillary Thyroid Carcinoma of a Large Thyroglossal Duct Cyst: A Case Report

Singh,

Ningshen,

Leishangthem

et al. 2024

IJMSCRS

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Background: Thyroglossal duct cyst is the most common congenital anomaly of the thyroid gland. Carcinoma arising from it is rare which composes 1% of total cases, often diagnosed incidentally after surgical excision. Here we are reporting a case of papillary thyroid carcinoma of thyroglossal cyst in 45-year-old female with normal thyroid gland. Case Description: A 45-year-old female presented with 1 year history of swelling over midline of the neck with normal thyroid gland. FNAC suggested a benign cystic lesion, most likely thyroglossal cyst. CT scan neck showed a well-defined lobulated and septated thin-walled cystic lesion of approx. 6×4×5cm in the midline upper infrahyoid region anterosuperior to thyroid, suggestive of thyroglossal cyst. Sistrunk procedure was performed. HPE revealed papillary thyroid carcinoma of thyroglossal cyst. Conclusion: A case of thyroglossal duct cyst with normal thyroid gland and without any clinical or radiological evidence of malignancy, a possibility of underlying malignancy should be kept in mind and can be managed adequately with Sistrunk procedure only, with regular follow up.

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Section: Discussionmentioning

confidence: 99%

Papillary Thyroid Carcinoma of a Large Thyroglossal Duct Cyst: A Case Report

Singh,

Ningshen,

Leishangthem

et al. 2024

IJMSCRS

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“…21 Metastatic spread is uncommon, and the prognosis is usually good. 15,26 Regional lymph node metastasis of thyroglossal duct carcinoma occurs only in 7% cases and local spread is usually rare. 9 Careful long term follow-up of papillary carcinoma of thyroglossal duct carcinoma is very important as it is a low grade malignancy and recurrences can be treated adequately with adequate follow-up.…”

Section: Pathological Discussionmentioning

confidence: 99%

Papillary Carcinoma Thyroid in Thyroglossal Cyst- A Case Report

Rao¹,

Rao²,

Kumar³

et al. 2019

jebmh

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“…Metastatic spread is very uncommon, and the prognosis is usually very good [ 15 , 27 ]. In a review by Patel et al, with a median follow-up of 71 months, the 5-year and 10-year Kaplan-Meier overall survival (OS) was 100% and 95.6%, respectively [ 28 ].…”

Section: Discussionmentioning

confidence: 99%

Invasive Thyroglossal Duct Cyst Papillary Carcinoma: A Case Report and Review of the Literature

et al. 2018

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Patient: Female, 27Final Diagnosis: Invasive thyroglossal duct cyst papillary carcinomaSymptoms: Painless cervical enlargementMedication: —Clinical Procedure: Sistrunk’s procedureSpecialty: SurgeryObjective:Rare diseaseBackground:Thyroglossal duct cyst is a common congenital anomaly of the thyroid gland, usually found centrally. The presence of malignancy occurring in a thyroglossal duct cyst is a rare condition, accounting only for 1% of all cases of thyroglossal duct cyst. This report is of a rare case of papillary carcinoma arising in a thyroglossal duct cyst and includes a review of the literature.Case Report:A 27-year-old female patient was referred to our department with a painless cystic mass in the neck. After initial physical examination and endocrinology investigations, a fine needle aspiration (FNA) of the cyst was performed. Cytology showed a papillary neoplasm. The patient underwent total thyroidectomy and surgical excision of the thyroglossal duct cyst (the Sistrunk’s procedure). Histopathology of the surgical excision specimen showed a thyroglossal duct cyst with a maximum diameter of 7.5 cm containing a primary invasive papillary carcinoma, measuring 1.5 cm in diameter that infiltrated into the cyst wall. The remaining thyroid gland was normal.Conclusions:Thyroglossal duct carcinoma, most commonly papillary carcinoma, is a rare condition that should be considered in patients presenting with cystic midline neck masses. Surgery and complete excision is the main treatment and the optimal patient management includes multidisciplinary consultation in order to improve survival. The diagnosis of malignancy is made postoperatively, as in the present case.

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Papillary Carcinoma Thyroid in a Thyroglossal Cyst

Cited by 3 publications

References 15 publications

Papillary Thyroid Carcinoma of a Large Thyroglossal Duct Cyst: A Case Report

Papillary Thyroid Carcinoma of a Large Thyroglossal Duct Cyst: A Case Report

Papillary Carcinoma Thyroid in Thyroglossal Cyst- A Case Report

Invasive Thyroglossal Duct Cyst Papillary Carcinoma: A Case Report and Review of the Literature

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