Papillary carcinoma arising from the pyramidal lobe of the thyroid gland – Two case reports

Papavramidis, Theodossis S; Zisi, Anna; Tzorakoleftheraki, Sofia-Eleni; Κoletsa, Triantafyllia; Pliakos, Ioannis; Panidis, Stavros; Kotsovolis, G; Manani, Christina; Kita, Marina; Michalopoulos, Antonios

doi:10.1016/j.jecr.2017.10.001

Cited by 1 publication

(2 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The use of FNAC as a preoperative diagnostic for malignancies is now common. Only a few cases of cancer in TGDC were detected preoperatively (7). Preoperatively, the reported case had a morphologically normal thyroid gland in the HRUS, a normal CT scan, and normal biochemical tests.…”

Section: Discussionmentioning

confidence: 83%

“…If the cyst becomes hard, fixed, irregular, or suddenly expands with palpable neck lymph nodes, malignancy should be suspected. Meanwhile, a CT or MRI scan may reveal a solid mass with invasive characteristics such as local invasion, hyoid bone infiltration, and cyst calcification (6,7). The use of FNAC as a preoperative diagnostic for malignancies is now common.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Papillary Thyroid Carcinoma Arising in Thyroglossal Duct Cyst and Locally Infiltrated to Hyoid Bone: Issue of Individualized Management

Dinu¹,

Begum

Bailey

et al. 2023

Bangladesh J. Nuclear Med.

View full text Add to dashboard Cite

Thyroglossal duct cyst (TGDC) is the most common developmental anomaly of the thyroid gland, while TGDC carcinoma with local infiltration to the hyoid bone is extremely rare. The reported case of papillary thyroid carcinoma (PTC) was diagnosed in TGDC along with local infiltration to the hyoid bone and needed individualized management. A 70-year-old male patient presented with a history of PTC arising in TGDC and locally infiltrated to the hyoid bone followed by total thyroidectomy and radical sistrunk operations and was referred to National Institute of Nuclear Medicine and Allied Sciences (NINMAS) for radioactive iodine therapy (RAIT). His post-operative ultrasound of the neck revealed an irregular shaped, fungating, grossly non-homogenous mixed echogenic mass lesion invading the hyoid bone, measuring about 25 X 28 mm. Radioactive iodine(131I) of 150 mCi was administered because the residual hyoid bone mass was inoperable and he was on thyroxine suppression therapy. The post-therapy 131I scan (RxWBS) showed two intense foci of radiotracer concentration (RTC) in the upper area (above the thyroid bed) and an intense focal RTC in the fundal region of the stomach. The activity in the stomach region was evaluated by ultrasound imaging, which revealed a soft tissue mass or thickening of the mid-region of the posterior wall of the stomach (3.3 cm X 1.6 cm). A CT scan of the chest was also performed to rule out metastasis, and it revealed multiple nodular lesions in both lung fields (most likely secondary) as well as tiny subcentric lymphnodes in the lower pre- and right paratracheal regions after nearly one month of RAIT when the patient was stable for examination. EBRT is still under consideration as adjuvant therapy. Tyrosine kinase inhibitors (TKI) may be considered in cases of refractoriness to radioiodine and disease progression. Bangladesh J. Nuclear Med. 26(1): 67-70, 2023

show abstract

Section: Discussionmentioning

confidence: 83%

Section: Discussionmentioning

confidence: 99%