Introduction: Adenocarcinoma of the fourth part of the duodenum is rare, and patients often present with a long history of non-specific symptoms, sometimes with advanced disease.
Case Report:We report the case of a 41-year-old male patient presenting with symptoms of upper gastrointestinal obstruction. Investigations included upper gastrointestinal (GI) endoscopy, barium followthrough, ultrasound, and computed tomography, which indicated gastric outlet obstruction. The precise nature of the lesion was subsequently revealed following diagnostic laparoscopy and laparotomy where an obstructing mass involving the duodenojejunal junction was identified. Segmental resection with a 2 cm safety margin, end to side anastomosis, and feeding jejunostomy was performed, and the lesion was confirmed as adenocarcinoma with free surgical margins. The patient made a good postoperative recovery with one year follow-up oesophagogastroduodenoscopy (OGD) and computed tomography (CT) scan, excluding local or nodal recurrence.
Conclusion:A high index of suspicion coupled with appropriate investigation and early surgical resection is necessary to manage the disease and improve prognosis.