Paper based integrated microfluidic system using electro-osmotic pumps with liquid bridges

Celik, Ahmet Yasin; Kaya, Kerem; Mutlu, Senol

doi:10.1109/memsys.2018.8346784

Cited by 2 publications

(4 citation statements)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We optimized design parameters of paper based EOPs with liquid bridges in our previous work [5]. We still had significant pressure-driven flows with the typical Whatman filter paper (average 10 μm pore size) used in that work [6,7].…”

Section: Design and Optimizationmentioning

confidence: 99%

“…EOPs are fabricated by patterning wax on membrane filter using a thermal nozzle attached to a three-axis CNC router as in our previous work [5]. Then, this paper is attached to the bottom PMMA plate using double-sided tape.…”

Section: Fabricationmentioning

confidence: 99%

“…To eliminate these limitations, porous plug EOP's [2,3] and liquid bridge connections [4] were suggested before. Similar to these works, we introduced paper based EOPs recently, which use paper as porous medium [5]. Paper-based EOPs can offer simple, compact and lightweight pumping solutions to the microfluidic systems mentioned above if their porous channels can be integrated to continuous microfluidic channels.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Integration of Paper Based Electro-Osmotic Pumps to Continuous Microfluidic Channels

2018

Self Cite

View full text Add to dashboard Cite

This work reports for the first-time integration of continuous microfluidic channels to the paper-based electro-osmotic pumps (EOPs) with liquid bridges. In addition, 0.2 μm pore sized cellulose acetate (CA) membrane filter is used to eliminate pressure-driven flow instead of filter paper which is common in paper microfluidics and has an average pore size of 10 μm. A factor of 57 increase in hydraulic resistance is achieved with the new paper. Fabrication of the pumps and microfluidic channels using paper, wax, adhesive film and PMMA plates is explained. Volumetric flow rate of 19 nL/min is achieved in the microfluidic system with 61 V/cm electrical field magnitude applied to DI water. The capability of the integrated system is shown with precise liquid motion in a Y-shaped microfluidic channel integrated with two EOPs.

show abstract

Section: Design and Optimizationmentioning

confidence: 99%

Section: Fabricationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Integration of Paper Based Electro-Osmotic Pumps to Continuous Microfluidic Channels

2018

Self Cite

View full text Add to dashboard Cite

show abstract

“…This is mainly due to the large difference between the maximum voltage of standard CMOS circuits and the voltage needed to drive EOF micropumps. While MEMS micropumps based on electrostatic, piezoelectric or thermopneumatic actuators require voltages ranging from 5 V to 200 V to obtain high flow rate [30]- [33], EOF micropumps typically require voltages higher than 40 V [22], [24] up to several 100 V [23], [26], as shown in Fig. 2a.…”

Section: Introductionmentioning

confidence: 99%

On-Chip CMOS-MEMS-Based Electroosmotic Flow Micropump Integrated With High-Voltage Generator

Okamoto

Ryoson

Fujimoto

et al. 2020

J. Microelectromech. Syst.

View full text Add to dashboard Cite

The rapid development of microfluidic technology has increased the demand for the integration of driving circuits in the microfluidic devices. We have proposed a novel on-chip electroosmotic (EOF) micropump integrated with a high-voltage (HV) generator. The HV (49.8 V) generator is based on a Dickson charge pump, which is fabricated on a silicon-on-insulator (SOI) substrate by the standard CMOS process, and the isolation is achieved by MEMS post-processed deep trench isolation. The size of the 49.8 V generator is 425×353 µ m 2 . The HV required for the successful operation of the micropump was generated by the integrated driving circuit with a low-voltage power supply. The maximum flow velocity and flow rate of the proposed EOF micropump were measured as 137 µ m/s and 167 nL/min, respectively when it was driven by the integrated 49.8 V generator. The efficiency of the micropump is demonstrated by comparing it with the previously reported micropumps. The proposed integration technique is reliable and effective, and potentially boosts the practical applications of lab-on-chip devices.

show abstract

Paper based integrated microfluidic system using electro-osmotic pumps with liquid bridges

Cited by 2 publications

References 6 publications

Integration of Paper Based Electro-Osmotic Pumps to Continuous Microfluidic Channels

Integration of Paper Based Electro-Osmotic Pumps to Continuous Microfluidic Channels

On-Chip CMOS-MEMS-Based Electroosmotic Flow Micropump Integrated With High-Voltage Generator

Contact Info

Product

Resources

About