Paper-based gold nanoparticles decorated SWCNTs chemiresistive sensor for sensitive detection of As(III) based on electrochemical doping

Zhao, Guo; Shen, Yu; Pham, Tung; Chen, Ying; Mulchandani, Ashok

doi:10.1016/j.aca.2022.340553

Cited by 16 publications

(8 citation statements)

References 36 publications

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“…To maintain device stability and minimize electrical noise, a commonly used reference electrode such as Ag/AgCl, Ag wire, or Pt wire is used as a solution gate controller and is kept at ground potential. [64][65][66] CNTs act as a sensing element in the FET device, which differs from conventional planar FETs, and their enhanced sensitivity is attributed to their reduced dimensionality and large surface-to-volume ratio, making them highly responsive to any electric bias imposed on the nanowire interface. In p-type nanobiosensors, the receptors on the nanowire interface capture positively charged analytes, resulting in an excess of holes that dominate the CNTs-FET.…”

Section: Cnt-based Fet Biosensor Working Principlementioning

confidence: 99%

Recent advances in Carbon Nanotube Based Field-Effect Transistor Biosensors for Established Biomarkers for the Diagnosis of Alzheimer's Disease

Shen

2023

Preprint

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Alzheimer's disease (AD) is a neurodegenerative disorder that affects millions of people worldwide. Early screening is crucial to prevent potential damages, and researchers are exploring alternative approaches such as multiplexed assays and emerging technologies such as microfluidics, nanotechnology, and biosensors. Current mainstream and conventional tests for AD biomarkers have limitations due to their insufficient sensitivity, which has led to the development of next-generation biosensing techniques that use nanomaterial-based field-effect transistors (FETs) for high-sensitivity and high-integration label-free biosensing. This review provides an overview of AD biomarkers, the working principle of FET biosensors, recent advances in CNT-based FET biosensors for the detection of AD biomarkers, and their potential for clinical diagnosis. FET biosensors have the potential to revolutionize the clinical detection of AD biomarkers, but there are challenges that need to be addressed for their successful translation into practical applications. In this review, we will provide an overview of the current understanding of AD biomarkers, describe the working principle of FET biosensors, and highlight recent advances in the development of CNT-based FET biosensors for the detection of AD biomarkers, with a particular emphasis on Aβ and tau proteins. We will also discuss the potential of these biosensors for clinical diagnosis and the challenges that need to be addressed for their successful translation into practical applications.

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Section: Cnt-based Fet Biosensor Working Principlementioning

confidence: 99%

Recent advances in Carbon Nanotube Based Field-Effect Transistor Biosensors for Established Biomarkers for the Diagnosis of Alzheimer's Disease

Shen

2023

Preprint

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“…[39][40][41] Among these mediators, ferrocene is commonly used because of its fast reaction with the enzyme, wide range of pH settings, and reversible electron kinetics. [42][43][44] Second-generation glucose sensors, utilizing a redox couple or mediator-based approach, have outperformed first-generation sensors since 1984 due to their sensitivity to dissolved oxygen, even at lower potentials and extreme interference ambience. The commercial product was made possible by the discovery of a screen-printing process that enabled the creation of wearable, disposable, compact, and pocket-friendly electrodes.…”

Section: Glucose Monitoring: the Sensing Mechanismsmentioning

confidence: 99%

Recent Advances in Graphene-Based Electrical Glucose Monitoring

Liu¹

2023

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The WHO notes that diabetes can contribute to various health problems, such as blindness, lethargy, kidney failure, strokes, numbness, and heart attacks. Diabetes can be an even worthy- noting problem in developing countries. In many developing countries, there has been significant economic growth over the past decade, but current projections indicate a slowing of this trend. Thus, it is crucial to prevent missed diagnoses and delayed treatment, as these could lead to fatal consequences. Regular glucose monitoring is an indispensable diagnostic tool that allows doctors to identify early symptoms of diabetes and administer timely treatment to avert severe complications. This review provides a peek into the basics of graphene, as well as the very recent advances since 2020 utilizing graphene, GO, rGO, and other novel graphene composite to monitor glucose.

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“…A new paper-based chemiresistive sensor has been developed for the detection of As(III) using a network of single-walled carbon nanotubes (SWCNTs) with electrodeposited gold nanoparticles (AuNPs). 59 The sensor was fabricated using a water-based SWCNT ink by wax printing and vacuum deposition. The sensitivity of the sensor was improved by optimizing the volume of SWCNTs ink used in the formation of the sensing network and the sweep segment of cyclic voltammetry used for the electrochemical deposition of AuNPs.…”

Section: Detection Of Heavy Metal Ionsmentioning

confidence: 99%

Paper-Based Electrical Sensors for Aqueous Heavy Metal Ion Detections

Sun¹,

Chen²,

Wong³

2023

Preprint

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Trace levels of heavy metals such as lead, cadmium, mercury, and arsenic can have harmful effects on human health, causing damage to organs and the nervous system. As a result, it is essential to monitor heavy metal concentrations continuously and in real-time, with detection limits of less than nanomolar to reduce their impact on the environment and human health. The development of paper-based microfluidics in recent years has made it a promising platform for lab-on-a-chip devices capable of detecting heavy metals on a large scale and on-site for environmental purposes. This review article will introduce commonly used paper-based electrical sensing (including electrochemical, FETs, and chemiresistive sensors), existing fabrication and analysis techniques, and various application areas for these heavy metal ion sensors. Additionally, the challenges that must be addressed for paper-based sensors to realize their full potential and future outlooks will be discussed.

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Paper-based gold nanoparticles decorated SWCNTs chemiresistive sensor for sensitive detection of As(III) based on electrochemical doping

Cited by 16 publications

References 36 publications

Recent advances in Carbon Nanotube Based Field-Effect Transistor Biosensors for Established Biomarkers for the Diagnosis of Alzheimer's Disease

Recent advances in Carbon Nanotube Based Field-Effect Transistor Biosensors for Established Biomarkers for the Diagnosis of Alzheimer's Disease

Recent Advances in Graphene-Based Electrical Glucose Monitoring

Paper-Based Electrical Sensors for Aqueous Heavy Metal Ion Detections

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