Paper-based enzymatic reactors for batch injection analysis of glucose on 3D printed cell coupled with amperometric detection

Dias, Anderson A.; Cardoso, Thiago da Silva Gusmão; Cardoso, Rafael M.; Duarte, Lucas C.; Muñoz, Rodrigo A.A.; Richter, Eduardo M.; Coltro, Wendell K. T.

doi:10.1016/j.snb.2015.11.040

Cited by 62 publications

(34 citation statements)

References 61 publications

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“…[19] The portable characteristics of both BIA and SPEs were already recognized forming a robust portable electrochemical system. Despite the large size of conventional BIA cells, analyses are possible with minimal sample volumes, such as 20 μL [19] or 10 μL, [21] which is not the case for conventional FIA or SIA (due to the need for higher volume), therefore, a microfluidic FIA or BIA system needs to be arranged. However, in this case, additional difficulties appear, such as greater internal pressure (leakages) and easy clogging.…”

Section: -Nitro-p-phenylenediaminementioning

confidence: 99%

“…The attractive features of the BIASPE system were also explored for the on-site determination of carbendazim, catechol and hydroquinone in tap water, [20] metals (Zn 2 + , Cd 2 + , Pb 2 + , Cu 2 + , and Hg 2 + ) in biodiesel samples, [85] glucose in artificial serum sample, [21] antioxidant 2,6-di-tert-butylphenol (2, in biodiesel and jet-fuel using hydro-organic media as the supporting electrolyte, [26] lead in aviation fuel samples, [86] omeprazole in pharmaceutical samples, [87] corrosion inhibitors (2,5-dimercapto-1,3,5-thiadiazole) in fuel ethanol, seawater and mineral oil samples, [88] levamisole and sodium levothyroxine in pharmaceutical samples, [89] nitrite and uric acid in biological fluids (urine, plasma, saliva, and serum), [90] antioxidant capacity of edible oil samples, [91] benzocaine and tricaine in fish fillets, [92] and a robust electroanalytical system for detection of UVinduced DNA degradation. [93] Recently, Mendonça et al [94] reported a low-cost mechanized system fabricated using fused deposition modelling 3D-printing technology to perform injections on an electrochemical cell in wall-jet configuration (similar to a common BIA cell).…”

Section: -Nitro-p-phenylenediaminementioning

confidence: 99%

“…Over recent years, many research groups have successfully demonstrated that homemade flowcells with different designs can be constructed and used for the positioning of SPEs. Flow-cells for FIA, [13][14][15][16][17][18] BIA, [19][20][21] and HPLC [22] systems are available in the literature. However, to attract potential new users, it is very important that a robust and easy to use flow systems for SPEs are commercially available.…”

Section: Introductionmentioning

confidence: 99%

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An Overview of Recent Electroanalytical Applications Utilizing Screen‐Printed Electrodes Within Flow Systems

et al. 2020

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This review addresses the use of screen-printed electrodes (SPEs) coupled to flow systems such as flow injection analysis (FIA), batch injection analysis (BIA), and high-performance liquid chromatography (HPLC) systems over the last six years (since 2014). The combination of SPEs and flow systems is a powerful synergy to increase the throughput of measurements, improve electrode lifetime, and reduce reagent consumption and waste generation. Recently, commercial flow cells for SPEs were made available by different companies and potential new users that are unable to construct homemade electrochemical flow cells have been attracted to work in the area. This overview aims to show both trends and future potential for the development of new methods useful for modern electroanalysis and/or portable applications.

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Section: -Nitro-p-phenylenediaminementioning

confidence: 99%

Section: -Nitro-p-phenylenediaminementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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An Overview of Recent Electroanalytical Applications Utilizing Screen‐Printed Electrodes Within Flow Systems

et al. 2020

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“…A polyvinyl alcohol-bound glass fiber was used to separate whole blood and the linear calibration range was from 0 up to 33.1 mM with a correlation coefficient of 0.987. Dias et al [120] developed a paper-based enzymatic device to detect glucose in the 3D batch injection analysis (BIA) cell coupled with SPEs. The LOD was 0.11 mM and linear range was 1–10 mM.…”

Section: Electrochemical Detection Of Glucosementioning

confidence: 99%

A Review on Microfluidic Paper-Based Analytical Devices for Glucose Detection

Liu

2016

Sensors

109

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Glucose, as an essential substance directly involved in metabolic processes, is closely related to the occurrence of various diseases such as glucose metabolism disorders and islet cell carcinoma. Therefore, it is crucial to develop sensitive, accurate, rapid, and cost effective methods for frequent and convenient detections of glucose. Microfluidic Paper-based Analytical Devices (μPADs) not only satisfying the above requirements but also occupying the advantages of portability and minimal sample consumption, have exhibited great potential in the field of glucose detection. This article reviews and summarizes the most recent improvements in glucose detection in two aspects of colorimetric and electrochemical μPADs. The progressive techniques for fabricating channels on μPADs are also emphasized in this article. With the growth of diabetes and other glucose indication diseases in the underdeveloped and developing countries, low-cost and reliably commercial μPADs for glucose detection will be in unprecedentedly demand.

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“…37 De modo alternativo, células eletroquímicas hidrodinâ-micas para SPE de custo muito menor podem ser confeccionadas em laboratório com o uso de microrretífica, 38 tornearia 35 ou impressão 3D. 39 Apesar da praticidade e rapidez destes sistemas hidrodinâmicos com SPE, existem poucos trabalhos na literatura para determinação de fármacos em medicamentos por FIA-SPE [40][41][42][43] e BIA-SPE. 43 Dessa forma, este trabalho propõe a determinação de CS empregando SPE em sistemas BIA e FIA com detecção amperométrica, sendo avaliados cinco SPE de diferentes eletrodos de trabalho.…”

Section: Introductionunclassified

Determinação rápida e simples de citrato de sildenafila (Viagra® e genéricos) empregando eletrodo impresso de carbono em sistemas FIA e BIA com detecção amperométrica

et al. 2017

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Screen Printed Electrodes (SPE). In BrittonRobinson buffer solution (pH 2), the SC presented an irreversible anodic peak at around +1.0 V vs. Ag pseudo-reference electrode, using five different working electrodes of commercial SPE. The carbon SPE (unmodified) was selected as the best working electrode, providing good sensitivity, precision and low-cost. The SC amperometric detection for two proposed methods was performed at +1.1 V. The best conditions for SC determination by hydrodynamic systems were obtained through injection volumes of 50 and 150 µL at flow rates of 100 and 75 µL s -1 , for BIA and FIA respectively. In these conditions, BIA system showed the best sensitivity (0.188 µA mol -1 L) and theoretical analytical frequency (360 h -1) for SC determination. The repeatability studies were similar for both systems with relative standard deviation of approximately 3.0%. The SC analyses in pharmaceutical samples obtained by two proposed methods were compared to HPLC-UV method. 1 Após expirar a patente do Viagra ® no Brasil em 2010, vários laboratórios passaram a produzir medicamentos genéricos e similares com CS, além de suas formulações manipuladas pelas farmácias magistrais. Apesar da redução do custo dos medicamentos em virtude desta concorrência, a aquisição de formulações falsificadas e contrabandeadas no mercado negro é um problema recorrente no Brasil, com predominância para o medicamento Pramil fabricado no Paraguai. Até o presente momento, não há nenhum método analítico oficial descrito pela Farmacopeia Brasileira ou pelos compêndios internacionais para o controle de qualidade de formulações de CS. Na literatura são reportados vários trabalhos para análise de CS em amostras farmacêuticas por métodos cromatográficos, principalmente, por Cromatografia Líquida de Alta Eficiência (HPLC, High Performance Liquid Chromatography).3-8 Apesar da robustez desses métodos na determinação de SC em amostras farmacêuticas, o custo elevado das análises e o maior tempo requerido nestes protocolos são inconvenientes para um controle de qualidade de rotina nas indústrias farmacêuticas. Além disso, esses métodos cromatográficos utilizam solventes orgânicos na composição da fase móvel, gerando grandes quantidades de resíduos tóxicos. Neste sentido, na literatura são descritos outros métodos que buscam contornar esses problemas para determinação de CS em medicamentos, como por exemplo, utilizando a eletroforese capilar 9 , espectrofotometria UV-VIS, [10][11][12][13][14][15] dispersão de Rayleigh 16 e, em destaque, o eletroanalítico devido à sua alta sensibilidade, seletividade e baixo custo de instrumentação. 17-28Dentre esses métodos eletroanalíticos para a determinação de CS, as técnicas voltamétricas de pulso diferencial e onda quadrada são as mais aplicadas usando diversos eletrodos de trabalho, como por exemplo: gota pendente de mercúrio, 17 (SPE, Screen-Printed Electrode). 26,27 Apesar do sucesso destes métodos, a maioria dos eletrodos sólidos utilizados nesses trabalhos está sujeita à passivação (envenenamento) d...

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Paper-based enzymatic reactors for batch injection analysis of glucose on 3D printed cell coupled with amperometric detection

Cited by 62 publications

References 61 publications

An Overview of Recent Electroanalytical Applications Utilizing Screen‐Printed Electrodes Within Flow Systems

An Overview of Recent Electroanalytical Applications Utilizing Screen‐Printed Electrodes Within Flow Systems

A Review on Microfluidic Paper-Based Analytical Devices for Glucose Detection

Determinação rápida e simples de citrato de sildenafila (Viagra® e genéricos) empregando eletrodo impresso de carbono em sistemas FIA e BIA com detecção amperométrica

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