Paper-based analytical devices for environmental analysis

Meredith, Nathan A.; Quinn, Casey; Cate, David M.; Reilly, Thomas H.; Volckens, John; Henry, Charles S.

doi:10.1039/c5an02572a

Cited by 253 publications

(141 citation statements)

References 171 publications

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“…Among the various microfluidic devices, microfluidic paper-based analytical devices (μPADs) have became a subject of research activities attributing to their advantages of cost effectiveness, disposability, simple fabrication, low sample volume required, and wettability (which helps eliminate external flow control systems) and ease of storage and delivery without damage (Cheng et al, 2010;Liana et al, 2012;Lisowski and Zarzycki 2013;Meredith et al, 2016). Unlike lateral flow assays which are difficult to obtain multiplex and qualitative results, μPADs can simultaneously detect multiple analytes from extracted samples and receive qualitative results via a scanner or smartphone (Parolo and Merkoçi 2013).…”

Section: Microfluidic Paper-based Analytical Devicementioning

confidence: 99%

A mini-review on functional nucleic acids-based heavy metal ion detection

Zhan

Wang

et al. 2016

Biosensors and Bioelectronics

143

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Section: Microfluidic Paper-based Analytical Devicementioning

confidence: 99%

A mini-review on functional nucleic acids-based heavy metal ion detection

Zhan

Wang

et al. 2016

Biosensors and Bioelectronics

143

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“…These traditional methods require expensive and/or complicated equipment and long, laboratory-based analysis. Several fast, low-cost sensors have been proposed for metal detection [16–21]. Recently, we have achieved colorimetric detection for Ni in particulate matter (PM) with microfluidic paper-based analytical devices (μPADs) [18, 22, 23].…”

Section: Introductionmentioning

confidence: 99%

Low-cost reusable sensor for cobalt and nickel detection in aerosols using adsorptive cathodic square-wave stripping voltammetry

Mettakoonpitak

Miller-Lionberg

Reilly

et al. 2017

Journal of Electroanalytical Chemistry

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A low-cost electrochemical sensor with Nafion/Bi modification using adsorptive stripping voltammetry for Co and Ni determination in airborne particulate matter and welding fume samples is described. Carbon stencil-printed electrodes (CSPEs) manufactured on low-cost PET films were utilized. Dimethylglyoxime (DMG) was used as a Co(II) and Ni(II) chelator with selective chemical precipitation for trace electrochemical analysis. Electrochemical studies of the Nafion/Bi-modified CSPE indicated a diffusion-controlled redox reaction for Co and Ni measurements. The Nafion coating decreased the background current and enhanced the measured peak current. Repeatability tests based on changes in percent relative standard deviation (RSD) of peak current showed the electrode could be used at least 15 times before the RSD exceeded 15% (the reported value of acceptable repeatability from Association of Official Analytical Chemists (AOAC)) due to deterioration of electrode surface. Limits of detection were 1 μg L−1 and 5 μg L−1 for Co and Ni, respectively, which were comparable to electrochemical sensors requiring more complicated modification procedures. The sensor produced a working range of 1–250 and 5–175 μg L−1 for Co and Ni, respectively. Interference studies showed no other metal species interfered with Co and Ni measurements using the optimized conditions. Finally, the developed sensors were applied for Co and Ni determination in aerosol samples generated from Co rods and a certified welding-fume reference material, respectively. Validation with ICP-MS showed no statistically different results with 95% confidence between sensor and the ICP methods.

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“…10,12 Onsite analysis was made more accessible through the fabrication of electrochemical PADs in comparison to the more traditional method of electrochemical detection that involves complicated and bulky instruments, which are not portable for the purpose of onsite analysis. Environmental analysis usually scans for heavy metals and toxic contaminants, which are often linked to excessive pollution from surplus of insecticides, pesticides and factory waste.…”

Section: ·2 Environmentalmentioning

confidence: 99%

“…However, in order to push more electrochemical PADs into commercial markets, development of multiplexed tests on PADs are highly desirable. 12 This is because sample treatment steps such as collection, storage, separation, extraction, concentration and analysis can be carried out in a single multiplexed sensor, which will further facilitate electrochemical detection. 13 Ultra-sensitive and high-throughput electrochemical detection of cancer biomarkers, such as carcinoembryonic antigen (CEA), alpha-fetoprotein (AFP), cancer antigen 125 (CA 125) and carbohydrate antigen 153 (CA 153) have been made possible by fabricating sensors in a multiplexed manner.…”

Section: Introductionmentioning

confidence: 99%

Trends in Paper-based Electrochemical Biosensors: From Design to Application

et al. 2018

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Electrochemical bio-sensing using paper-based detection systems is the main focus of this review. The different existing designs of 2-dimensional and 3-dimensional sensors, and fabrication techniques are discussed. This review highlights the effect of adopting different sensor designs, distinct fabrication techniques, as well as different modification methods, in order to produce reliable and reproducible reading. The use of various nanomaterials have been demonstrated in order to modify the surface of electrodes during fabrication to further enhance the signal for subsequent analysis. The reviewed sensors were classified into categories based on their applications, such as diagnostics, environmental and food testing. One of the major advantages of using paper-based electrochemical sensors is the potential for miniaturization, which only requires relatively small amount of samples, and the low cost for the purpose of mass production. Additionally, most of the devices reviewed were made to be portable, making them well-suited for on-site detection. Finally, paper-based detection is an ideal platform to fabricate cost-effective, user-friendly and sensitive electrochemical biosensors, with large capacity for customization depending on functional needs.

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Paper-based analytical devices for environmental analysis

Cited by 253 publications

References 171 publications

A mini-review on functional nucleic acids-based heavy metal ion detection

A mini-review on functional nucleic acids-based heavy metal ion detection

Low-cost reusable sensor for cobalt and nickel detection in aerosols using adsorptive cathodic square-wave stripping voltammetry

Trends in Paper-based Electrochemical Biosensors: From Design to Application

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