Papel de la proteína C reactiva en las enfermedades cardiovasculares

Manzur, Fernando; Alvear, Ciro; Alayón, Alicia Norma

doi:10.1016/s0120-5633(11)70198-x

Cited by 6 publications

(5 citation statements)

References 39 publications

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“…From this diverse assortment of candidates, CRP appears to be the most profoundly studied regarding inflammation in the cardiovascular field [ 53 ]. Not only has CRP been associated with the chain of events occurring at the endothelium within the atherosclerotic process [ 54 , 55 ], but it has also been linked with a direct, independent association with future cardiovascular events in several great-scale epidemiologic reports [ 27 , 56 , 57 ], as well as with other disorders of metabolic origin, both in adult and pediatric populations [ 58 , 59 ].…”

Section: Cardiovascular Risk Factors: Classic Versus Novel ( mentioning

confidence: 99%

C-Reactive Protein: Clinical and Epidemiological Perspectives

Salazar

Martínez

Chávez-Castillo

et al. 2014

Cardiology Research and Practice

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An important etiopathogenic component of cardiovascular disease is atherosclerosis, with inflammation being an essential event in the pathophysiology of all clinical pictures it comprises. In recent years, several molecules implicated in this process have been studied in order to assess cardiovascular risk in both primary and secondary prevention. C-reactive protein is a plasmatic protein of the pentraxin family and an acute phase reactant, very useful as a general inflammation marker. Currently, it is one of the most profoundly researched molecules in the cardiovascular field, yet its clinical applicability regarding cardiovascular risk remains an object of discussion, considered by some as a simple marker and by others as a true risk factor. In this sense, numerous studies propose its utilization as a predictor of cardiovascular risk through the use of high-sensitivity quantification methods for the detection of values <1 mg/L, following strict international guidelines. Increasing interest in these clinical findings has led to the creation of modified score systems including C-reactive protein concentrations, in order to enhance risk scores commonly used in clinical practice and offer improved care to patients with cardiovascular disease, which remains the first cause of mortality at the worldwide, national, and regional scenarios.

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Section: Cardiovascular Risk Factors: Classic Versus Novel ( mentioning

confidence: 99%

C-Reactive Protein: Clinical and Epidemiological Perspectives

Salazar

Martínez

Chávez-Castillo

et al. 2014

Cardiology Research and Practice

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“…31,32 From 2000 to 2010, the prevalence of diabetes was of 1% to 22% (Tables 4 and 5). [33][34][35][36][37][38][39][40][41][42][43][44][45][46] Most recently, between 2011 and 2015, the prevalence of diabetes was 2% to 28.5% (Table 6). [47][48][49][50][51][52][53][54] Each of the regional epidemiologic studies cited here were influenced by certain Similarly, studies in school children, adolescents, and those aged <20 years reported a prevalence of T1D of 1.8% (with a 3.8% incidence in children aged 14 years) and a prevalence of fasting hyperglycemia between 0.7% and 11%.…”

Section: E T H O D Smentioning

confidence: 99%

An Epidemiologic Analysis of Diabetes in Colombia

Vargas‐Uricoechea

Figueroa

2015

Annals of Global Health

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“…La proteína C-reactiva es un reactante de fase aguda sintetizado en el hígado y su incremento está regulado por el aumento de citoquinas proinflamatorias, en especial, la interleucina 6 (IL-6) y en menor frecuencia, la interleucina 1 (IL-1) y el factor de necrosis tumoral α (TNFα, por sus siglas en inglés) que responden al daño inducido en los tejidos por inflamaciones, infecciones o neoplasias (6)(7)(8)(9) .…”

Section: Introductionunclassified

“…Se ha descrito que 6 a 12 horas después de empezar el estímulo inflamatorio, la proteína C-reactiva se incrementa y alcanza sus valores máximos entre las 24 a 72 horas, con una vida media de alrededor de 19 horas (8,9) . Acabado el estímulo, sus valores se normalizan a los 7 días, aproximadamente.…”

Section: Introductionunclassified

“…Acabado el estímulo, sus valores se normalizan a los 7 días, aproximadamente. Su índice de producción establece sus valores circulantes, reflejando la intensidad de los procesos patológicos que contribuyeron a su estímulo (9) . La proteína C-reactiva se liga a la fosfocolina y reconoce patógenos externos; además, inhibe la adhesión leucocitaria al endotelio y la generación de superóxidos en los neutrófilos y estimula la síntesis de factor tisular en los monocitos y citocinas inflamatorias (10) .…”

Section: Introductionunclassified

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Proteína C-reactiva asociada a la condición periodontal de gestantes

Sangay

Gómez²

2020

HorizMed

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Objetivo: Determinar el nivel de proteína C-reactiva según el estado periodontal, edad y trimestre de gestación en gestantes del Centro de Salud Magna Vallejo en Cajamarca, Perú. Materiales y métodos: Estudio observacional, descriptivo y transversal. Se trabajó con una muestra de 60 gestantes divididas en tres grupos: gestantes periodontalmente sanas, con gingivitis y con periodontitis. Se empleó el índice de Rusell para la determinación del estado periodontal. El valor del nivel de proteína C-reactiva fue tomado del registro de la historia clínica de cada paciente. Resultados: Se encontró un nivel de proteína C-reactiva elevado en el 66,70 % de gestantes con gingivitis y en el 100 % de gestantes con periodontitis, así mismo en el 84,60 % de gestantes adultas. Conclusiones: Los niveles de proteína C-reactiva tienden a elevarse en las pacientes con enfermedad periodontal y se incrementa con la edad de las gestantes.

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Papel de la proteína C reactiva en las enfermedades cardiovasculares

Cited by 6 publications

References 39 publications

C-Reactive Protein: Clinical and Epidemiological Perspectives

C-Reactive Protein: Clinical and Epidemiological Perspectives

An Epidemiologic Analysis of Diabetes in Colombia

Proteína C-reactiva asociada a la condición periodontal de gestantes

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