Papel de la presión de pulso, presión arterial sistólica y presión arterial diastólica en la predicción del riesgo cardiovascular. Estudio de cohortes

Baena-Díez, José Miguel; Bermúdez-Chillida, Noemí; García-Lareo, Manel; Byram, Alice O.; Vidal-Solsona, Marc; Vilató-García, Mónica; Gómez-Fernández, Claudia; Vásquez-Lazo, Javier Ernesto

doi:10.1157/13117460

Cited by 5 publications

(2 citation statements)

References 31 publications

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“…This distribution of DBP has previously been described for ischemic heart disease 33 . In Spain 34 , a reduction in the relative risk of cardiovascular disease has been described for values between 76 and 83 mmHg (RR = 0.75). The reduction is less intense for values ≥ 75 mmHg (RR = 0.88) with respect to DBP ≥ 84 mmHg.…”

Section: Discussionmentioning

confidence: 99%

Cardiovascular risk factors associated with acute myocardial infarction and stroke in the MADIABETES cohort

Salinero-Fort

Andrés-Rebollo

Cárdenas‐Valladolid

et al. 2021

Sci Rep

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We aimed to develop two models to estimate first AMI and stroke/TIA, respectively, in type 2 diabetes mellitus patients, by applying backward elimination to the following variables: age, sex, duration of diabetes, smoking, BMI, and use of antihyperglycemic drugs, statins, and aspirin. As time-varying covariates, we analyzed blood pressure, albuminuria, lipid profile, HbA1c, retinopathy, neuropathy, and atrial fibrillation (only in stroke/TIA model). Both models were stratified by antihypertensive drugs. We evaluated 2980 patients (52.8% women; 67.3 ± 11.2 years) with 24,159 person-years of follow-up. We recorded 114 cases of AMI and 185 cases of stroke/TIA. The factors that were independently associated with first AMI were age (≥ 75 years vs. < 75 years) (p = 0.019), higher HbA1c (> 64 mmol/mol vs. < 53 mmol/mol) (p = 0.003), HDL-cholesterol (0.90–1.81 mmol/L vs. < 0.90 mmol/L) (p = 0.002), and diastolic blood pressure (65–85 mmHg vs. < 65 mmHg) (p < 0.001). The factors that were independently associated with first stroke/TIA were age (≥ 75 years vs. < 60 years) (p < 0.001), atrial fibrillation (first year after the diagnosis vs. more than one year) (p = 0.001), glomerular filtration rate (per each 15 mL/min/1.73 m2 decrease) (p < 0.001), total cholesterol (3.88–6.46 mmol/L vs. < 3.88 mmol/L) (p < 0.001), triglycerides (per each increment of 1.13 mmol/L) (p = 0.031), albuminuria (p < 0.001), neuropathy (p = 0.01), and retinopathy (p = 0.023).

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Section: Discussionmentioning

confidence: 99%

Cardiovascular risk factors associated with acute myocardial infarction and stroke in the MADIABETES cohort

Salinero-Fort

Andrés-Rebollo

Cárdenas‐Valladolid

et al. 2021

Sci Rep

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“…In relation to the rs2010963 (−634 G/C) variant, we found a range of significant correlations between the serum VEGF-A level and functional and biochemical parameters: positive correlations with HR, DBP, and HDL serum level in the CC genotype in obese and overweight patients, and negative correlations with eGFR, also in group A, in the GG and CC genotypes. HR, DBP, serum HDL, and eGFR have been demonstrated to be markers of cardiovascular risk [41][42][43][44]. This suggests that, particularly in patients with the CC genotype, the synthesis of VEGF-A, and consequently the process of angiogenesis and endothelial dysfunction management, is susceptible to overall cardiometabolic status.…”

Section: Discussionmentioning

confidence: 99%

Association of rs699947 (−2578 C/A) and rs2010963 (−634 G/C) Single Nucleotide Polymorphisms of the VEGF Gene, VEGF-A and Leptin Serum Level, and Cardiovascular Risk in Patients with Excess Body Mass: A Case–Control Study

Skrypnik

Mostowska

Jagodzińśki

et al. 2020

JCM

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Clinical factors associated with peripheral artery disease in patients with documented coronary artery disease: A post hoc analysis of the COMPASS trial

et al. 2021

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Papel de la presión de pulso, presión arterial sistólica y presión arterial diastólica en la predicción del riesgo cardiovascular. Estudio de cohortes

Cited by 5 publications

References 31 publications

Cardiovascular risk factors associated with acute myocardial infarction and stroke in the MADIABETES cohort

Cardiovascular risk factors associated with acute myocardial infarction and stroke in the MADIABETES cohort

Association of rs699947 (−2578 C/A) and rs2010963 (−634 G/C) Single Nucleotide Polymorphisms of the VEGF Gene, VEGF-A and Leptin Serum Level, and Cardiovascular Risk in Patients with Excess Body Mass: A Case–Control Study

Clinical factors associated with peripheral artery disease in patients with documented coronary artery disease: A post hoc analysis of the COMPASS trial

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