Pantoea agglomerans: ¿un nuevo patógeno en la unidad de cuidados intensivos neonatales?

Segado-Arenas, Antonio; Alonso‐Ojembarrena, Almudena; Lubián‐López, Simón Pedro; García-Tapia, Ana

doi:10.5546/aap.2012.e77

Cited by 10 publications

(11 citation statements)

References 7 publications

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“…Prematurity and associated immature immune systems resulting in the relative immunocompromised state are the major risk factors for hospital-acquired infections due to Pantoea in newborn infants [10]. 75% (30 out of 40) of all neonatal Pantoea infections reported in the English literature as of July 2020 occurred in preterm infants [1,2,5,7,[11][12][13][14][15][16]. Most of these infants had at least one comorbid condition.…”

Section: Risk Factorsmentioning

confidence: 99%

Pantoea Infections in the Neonatal Intensive Care Unit

Mani

Nair

2021

Cureus

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Pantoea is a plant pathogen infrequently reported to cause opportunistic bloodstream infections. This gramnegative bacillus is a rare cause of hospital-acquired infections in newborn infants with high mortality. Since the creation of the new genus Pantoea in 1989, the evidence base available to neonatal health care providers is limited. Most of the available literature consists of case reports and case series. This review aims to consolidate the current reported literature on Pantoea infections, focusing on newborn infants and the neonatal intensive care unit (NICU). Prematurity and the associated relative immunocompromised state are major risk factors for hospital-acquired infections due to Pantoea in newborn infants. Recent advances in molecular biology have improved our understanding of the cross-kingdom pathogenesis exhibited by Pantoea. Respiratory symptoms and association with central venous lines are the most common clinical presentation of Pantoea bacteremia in newborn infants. Early institution of appropriate antibiotic therapy against this organism could be lifesaving. Therefore, it is critical for neonatologists to understand the clinical spectrum of Pantoea infections in NICUs.

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Section: Risk Factorsmentioning

confidence: 99%

Pantoea Infections in the Neonatal Intensive Care Unit

Mani

Nair

2021

Cureus

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“…In our study, the most representative species in A. aegypti population (control group) was P. agglomerans. It is common to find this bacterium as a symbiont in mosquitoes since it is a natural inhabitant of the environment (Segado Arenas et al, 2012;Mayer et al, 2017). In mosquitoes, this bacterium participates in nitrogen fixation, creating a nitrogenrich environment ideal for the development of eggs and larvae (MacCollom et al, 2009).…”

Section: Discussionmentioning

confidence: 99%

Suppression of Midgut Microbiota Impact Pyrethroid Susceptibility in Aedes aegypti

et al. 2022

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Aedes aegypti is a mosquito that transmits viral diseases such as dengue, chikungunya, Zika, and yellow fever. The insect’s microbiota is recognized for regulating several biological processes, including digestion, metabolism, egg production, development, and immune response. However, the role of the bacteria involved in insecticide susceptibility has not been established. Therefore, the objective of this study was to characterize the resident microbiota in a field population of A. aegypti to evaluate its role associated with susceptibility to the insecticides permethrin and deltamethrin. Mosquitoes were fed 10% sucrose mixed with antibiotics and then exposed to insecticides using a diagnostic dose. DNA was extracted, and sequencing of bacterial 16S rRNA was carried out on Illumina® MiSeq™. Proteobacteria (92.4%) and Bacteroidetes (7.6%) were the phyla, which are most abundant in mosquitoes fed with sucrose 10%. After exposure to permethrin, the most abundant bacterial species were Pantoea agglomerans (38.4%) and Pseudomonas azotoformans-fluorescens-synxantha (14.2%). Elizabethkingia meningoseptica (38.4%) and Ps. azotoformans-fluorescens-synxantha (26.1%) were the most abundant after exposure to deltamethrin. Our results showed a decrease in mosquitoes’ survival when exposed to permethrin, while no difference in survival when exposed to deltamethrin when the microbiota was modified. We found that the change in microbiota modifies the response of mosquitoes to permethrin. These results are essential for a better understanding of mosquito physiology in response to insecticides.

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“…These two bacterial species can be found in soil and water. Indeed, P. agglomerans can be frequently isolated from plants, fruits and vegetables, presenting pathogenicity more frequently in plants (Scheutz et al 2005, Segado-Arenas et al 2012. In addition, it also occurs in vertebrates and invertebrates, but its clinical importance in animals is almost unknown (Dutkiewicz et al 2016).…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial susceptibility profile of enterobacteria isolated from wild grey-breasted parakeets (Pyrrhura griseipectus)

et al. 2021

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The grey-breasted parakeet (Pyrrhura griseipectus) is an endangered psittacine species that have been affected by illegal trade and deforestation. Currently, this endemic species is only found in three areas in Ceará state, in Brazil. This study aimed to investigate the frequency and diversity of Enterobacteriaceae in wild adult grey-breasted parakeets and determine their susceptibility to antimicrobial agents. Cloacal swab samples were collected from 27 individuals and environmental swabs (drag swabs) from five nests used by these birds. Twenty-seven strains from nine species of Enterobacteriaceae were recovered from cloacal swabs, and the most prevalent bacteria strains were Hafnia alvei (22%) and Pantoea agglomerans (22%). From environmental nest samples, seven strains from three bacterial species were isolated, being the P. agglomerans the most frequent species (100%). Twenty-two of the 27 isolates (81.4%) exhibited antibiotic resistance, varying from one to eight of the 12 antimicrobials commonly used. Resistance to amoxicillin was the most prevalent (70.4%), followed by azithromycin (22.2%) and ceftriaxone (18.5%). None of the strains were resistant to gentamicin, tobramycin, ciprofloxacin or tetracycline. The H. alvei was the main species presenting multidrug resistance, including resistance against meropenem, which is an important finding. These results could provide interesting information on the health of these endangered wild grey-breasted parakeets. They could also indicate that the obtained isolates are part of a group of bacteria that are typical components of the enteric microbiota of birds, which present elevated rates of resistance to amoxicillin.

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Pantoea agglomerans: ¿un nuevo patógeno en la unidad de cuidados intensivos neonatales?

Cited by 10 publications

References 7 publications

Pantoea Infections in the Neonatal Intensive Care Unit

Pantoea Infections in the Neonatal Intensive Care Unit

Suppression of Midgut Microbiota Impact Pyrethroid Susceptibility in Aedes aegypti

Antimicrobial susceptibility profile of enterobacteria isolated from wild grey-breasted parakeets (Pyrrhura griseipectus)

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