Pantoea agglomerans Foreign Body–Induced Septic Arthritis

Rave, Omer; Assous, Marc V.; Hashkes, Philip J.; Lebel, Ehud; Hadas-Halpern, Irit; Megged, Orli

doi:10.1097/inf.0b013e31826fd434

Cited by 17 publications

(18 citation statements)

References 9 publications

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“…When we reviewed the literature, there was one synovitis, seven osteomyelitis, one periostitis, and six septic arthritis cases caused by P. agglomerans described between 1978 and 2019 (►Table 1). [4][5][6][7][8][9][10][11][12] Thirteen of 15 patients were boys (88%) and median age was 7.4 years. In most cases, diagnosis was delayed 4 to 6 weeks after trauma because of the low virulence of the bacterium and late recognition of the foreign body.…”

Section: Discussionmentioning

confidence: 99%

Pantoea agglomerans as a Cause of Foreign Body Related Septic Arthritis in a Child: Case Report and Review of the Literature

Demircan

Kasap-Demir

Şahin

et al. 2020

Journal of Pediatric Infectious Diseases

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A previously healthy 7-year-old female patient was admitted with pain and swelling in her left knee and fever. She had injured her left knee 2 weeks ago. Her mother had noticed a protrusion on her knee that she had thought to be associated with a fracture. After being examined by an orthopaedist, fracture was ruled out and the protrusion disappeared. On her admission with fever and painful swollen knee, Pantoea agglomerans was identified in the synovial fluid. On the basis of the close association of P. agglomerans infections with penetrating trauma, the patient and her mother were asked about a history of penetration during the fall, but they denied any possible penetration of a vegetative element since she had fallen on a concrete floor. Although she was treated with antibiotics reported to be sensitive in the antibiogram, she had recurrent septic arthritis. Repeated magnetic resonance imaging (MRI) interpretations revealed a foreign body in the medial aspect of the left knee. The patient underwent arthrotomy and a plant thorn was removed. The postoperative course was uneventful. We reported this case to emphasize that a vegetative foreign body should be kept in mind in septic arthritis caused by P. agglomerans and/or in those resistant to antibiotics. In addition, we reviewed the literature including children having joint and/or bone infections caused by P. agglomerans.

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Section: Discussionmentioning

confidence: 99%

Pantoea agglomerans as a Cause of Foreign Body Related Septic Arthritis in a Child: Case Report and Review of the Literature

Demircan

Kasap-Demir

Şahin

et al. 2020

Journal of Pediatric Infectious Diseases

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“…Wound infection with P. agglomerans could follow piercing or laceration of skin with a plant thorn, wooden splinter or other plant material, usually during performing of agricultural occupations [1,2], during gardening [3,4,5,6] or children playing [7,8,9,10,11,12,13], and subsequent inoculation of the plant-residing bacteria. Recently, Vaiman et al [14] found in a retrospective study that all 9 patients with 1-2 months of ineffective treatment of post-traumatic wounds showed the presence of foreign bodies of plant origin infected with Pantoea agglomerans.…”

mentioning

confidence: 99%

“…Septic arthritis or synovitis appears as a common clinical outcome of exogenous infection with P. agglomerans (Figs. [1][2] [4,5,7,9,10,11,12,13], others include endophthalmitis [3,6,15,16], acute unilateral dacryocystitis, peculiar by the kind of eye contaminant -not a plant material but dog feces [17], corneal infiltrate in an agricultural worker after rice husk injury, caused by Pantoea ananatis, a species closely related to P. agglomerans [18], periostitis [8], endocarditis [19], osteomyelitis after injury with rose thorn [20] or after closed fracture [21], tibial osteitis after an open grade IIIB tibial shaft fracture [22], and a tumour-like muscle cyst of the thigh [2].…”

mentioning

confidence: 99%

<i>Pantoea agglomerans</i>: a mysterious bacterium of evil and good. Part III. Deleterious effects: infections of humans, animals and plants

Dutkiewicz¹,

Maćkiewicz²,

Lemieszek³

et al. 2016

Ann Agric Environ Med.

175

122

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Pantoea agglomerans, a bacterium associated with plants, is not an obligate infectious agent in humans. However, it could be a cause of opportunistic human infections, mostly by wound infection with plant material, or as a hospital-acquired infection, mostly in immunocompromised individuals. Wound infection with P. agglomerans usually follow piercing or laceration of skin with a plant thorn, wooden splinter or other plant material and subsequent inoculation of the plant-residing bacteria, mostly during performing of agricultural occupations and gardening, or children playing. Septic arthritis or synovitis appears as a common clinical outcome of exogenous infection with P. agglomerans, others include endophthalmitis, periostitis, endocarditis and osteomyelitis. Another major reason for clinical infection with P. agglomerans is exposure of hospitalized, often immunodeficient individuals to medical equipment or fluids contaminated with this bacterium. Epidemics of nosocomial septicemia with fatal cases have been described in several countries, both in adult and paediatric patients. In most cases, however, the clinical course of the hospital-acquired disease was mild and application of the proper antibiotic treatment led to full recovery. Compared to humans, there are only few reports on infectious diseases caused by Pantoea agglomerans in vertebrate animals. This species has been identified as a possible cause of equine abortion and placentitis and a haemorrhagic disease in dolphin fish (Coryphaena hippurus). P. agglomerans strains occur commonly, usually as symbionts, in insects and other arthropods. Pantoea agglomerans usually occurs in plants as an epi-or endophytic symbiont, often as mutualist. Nevertheless, this species has also also been identified as a cause of diseases in a range of cultivable plants, such as cotton, sweet onion, rice, maize, sorghum, bamboo, walnut, an ornamental plant called Chinese taro (Alocasia cucullata), and a grass called onion couch (Arrhenatherum elatius). Some plant-pathogenic strains of P. agglomerans are tumourigenic, inducing gall formation on table beet, an ornamental plant gypsophila (Gypsophila paniculata), wisteria, Douglas-fir and cranberry. Recently, a Pantoea species closely related to P. agglomerans has been identified as a cause of bacterial blight disease in the edible mushroom Pleurotus eryngii cultivated in China. The genetically governed determinants of plant pathogenicity in Pantoea agglomerans include such mechanisms as the hypersensitive response and pathogenicity (hrp) system, phytohormones, the quorum-sensing (QS) feedback system and type III secretion system (T3SS) injecting the effector proteins into the cytosol of a plant cell.

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“…Consequently, penetrating plant parts should be carefully located and surgically removed to prevent high‐risk complications. In addition to localized infections immuno‐suppressed patients and neonates may also develop primary bacteriemias and systemic infections . Outbreaks of nosocomial infection have been reported in connection with contaminated parenteral nutrient products, infusions, catheters or blood products .…”

mentioning

confidence: 99%

“…In addition to localized infections immuno-suppressed patients and neonates may also develop primary bacteriemias and systemic infections. 4 Outbreaks of nosocomial infection have been reported in connection with contaminated parenteral nutrient products, infusions, catheters or blood products. 1 In addition to its importance in human medicine, Pantoea agglomerans is of great interest for agriculture.…”

mentioning

confidence: 99%

Pantoea agglomerans – an underestimated pathogenic agent in penetrating trauma involving vegetative material

Friedling

Kekulé

et al. 2015

Acad Dermatol Venereol

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Pantoea agglomerans Foreign Body–Induced Septic Arthritis

Cited by 17 publications

References 9 publications

Pantoea agglomerans as a Cause of Foreign Body Related Septic Arthritis in a Child: Case Report and Review of the Literature

Pantoea agglomerans as a Cause of Foreign Body Related Septic Arthritis in a Child: Case Report and Review of the Literature

<i>Pantoea agglomerans</i>: a mysterious bacterium of evil and good. Part III. Deleterious effects: infections of humans, animals and plants

Pantoea agglomerans – an underestimated pathogenic agent in penetrating trauma involving vegetative material

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