PANoptosis and Autophagy-Related Molecular Signature and Immune Landscape in Ulcerative Colitis: Integrated Analysis and Experimental Validation
Jiali Lu,
Fei Li,
Mei Ye
Abstract:Background: Ulcerative colitis (UC) is an autoimmune inflammatory disorder of the gastrointestinal tract. Programmed cell death (PCD), including PANoptosis and autophagy, plays roles in inflammation and immunity. This study aimed to investigate the molecular signature and immune landscape of the PANoptosis-and autophagy-related differentially expressed genes (DEGs) in UC. Methods: Analyzing UC dataset GSE206285 yielded DEGs. Differentially expressed PANoptosis-and autophagy-related genes were identified using … Show more
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