Panic attacks as a risk for later psychopathology: results from a nationally representative survey

Kinley, Jolene; Walker, John R.; Enns, Murray W.; Sareen, Jitender

doi:10.1002/da.20809

Cited by 41 publications

(33 citation statements)

References 43 publications

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“…Although depression commonly precedes manifestations of mania or hypomania in patients diagnosed with BPD [3,79,82], anxiety disorders or anxious depression may also be antecedents of later BPD, as well as being common comorbidities with BPD [6,28,30,89,90,91,92,93,94,95]. As we found (table 1; online suppl.…”

Section: Discussionsupporting

confidence: 48%

Excessive Mood Elevation and Behavioral Activation with Antidepressant Treatment of Juvenile Depressive and Anxiety Disorders: A Systematic Review

Offidani

Fava

Tomba

et al. 2013

Psychother Psychosom

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Background: The prevalence, characteristics and implications of excessive arousal-activation in children and adolescents treated with antidepressants for specific illnesses have not been systematically examined. Methods: We compared reports of antidepressant trials (n = 6,767 subjects) in juvenile depressive (n = 17) and anxiety disorders (n = 25) for consensus-based indications of psychopathological mood elevation or behavioral activation. Results: Rates of excessive arousal-activation during treatment with antidepressants were at least as high in juvenile anxiety (13.8%) as depressive (9.79%) disorders, and much lower with placebos (5.22 vs. 1.10%, respectively; both p < 0.0001). The antidepressant/placebo risk ratio for such reactions in paired comparisons was 3.50 (12.9/3.69%), and the meta-analytically pooled rate ratio was 1.7 (95% confidence interval: 1.2-2.2; both p ≤ 0.001). Overall rates for ‘mania or hypomania', specifically, were 8.19% with and 0.17% without antidepressant treatment, with large drug/placebo risk ratios among depressive (10.4/0.45%) and anxiety (1.98/0.00%) disorder patients. Conclusions: Risks of excessive mood elevation during antidepressant treatment, including mania-hypomania, were much greater than with placebo, and similar in juvenile anxiety and depressive disorders. Excessive arousal-activation in children or adolescents treated with antidepressants for anxiety as well as depressive disorders calls for particular caution and monitoring for potential risk of future bipolar disorder.

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Section: Discussionsupporting

confidence: 48%

Excessive Mood Elevation and Behavioral Activation with Antidepressant Treatment of Juvenile Depressive and Anxiety Disorders: A Systematic Review

Offidani

Fava

Tomba

et al. 2013

Psychother Psychosom

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“…The previously displayed relationships between PAs and a variety of types of psychopathology [43] were replicated in this study among Vietnamese typhoon survivors, although limited to posttyphoon PTSD and MDD, but not GAD.…”

Section: Discussionsupporting

confidence: 71%

Pretyphoon Panic Attack History Moderates the Relationship Between Degree of Typhoon Exposure and Posttyphoon PTSD and Depression in a Vietnamese Sample

et al. 2013

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Background Predisaster risk factors are related to postdisaster psychopathology even at relatively low levels of disaster exposure. A history of panic attacks (PA) may convey risk for postdisaster psychopathology and has been linked to a wide range of psychiatric disorders in Western and non-Western samples. The present study examined the main and interactive effects of pretyphoon PA and level of typhoon exposure in the onset of posttyphoon posttraumatic stress disorder (PTSD), major depression (MDD), and generalized anxiety disorder (GAD) in a Vietnamese sample of typhoon survivors. Methods Typhoon Xangsane interrupted a Vietnamese epidemiological mental health needs assessment, providing a rare opportunity for preand posttyphoon assessments. Hierarchical logistic regression analyses evaluated whether the main and interactive effects of typhoon exposure severity and PA history were significantly related to posttyphoon diagnoses, above and beyond age, health status, pretyphoon psychiatric screening results, and history of potentially traumatic events. Results PA history moderated the relationship between severity of typhoon exposure and posttyphoon PTSD and MDD, but not GAD. Specifically, greater degree of exposure to the typhoon was significantly related to increased likelihood of postdisaster PTSD and MDD among individuals without a history of PA, above and beyond variance accounted for by pretyphoon psychiatric screening results. Individuals with a history of PA evidenced greater risk for postdisaster PTSD and MDD regardless of severity of typhoon exposure. Conclusions Preexisting PA may affect the nature of the relationship between disaster characteristics and prevalence of postdisaster PTSD and MDD within Vietnamese samples.

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“…Anxiety in the past,18 19 family history,20 current depressive symptoms and role impairment,20 47 48 childhood adversities and traumatic events14 18 have been found to be risk factors for major depression. The PredictD algorithm for major depression among primary care patients also found that racial discrimination was predictive of the risk of major depression 20 48.…”

Section: Discussionmentioning

confidence: 99%

“…Psychosocial risk factors for MDE include negative life events, experience of traumatic events, work stress, financial strain, poor marital or interpersonal relationships, lack of social support, and low self-esteem and mastery 13–17. Individuals with anxiety in the past18 19 and those who have family history of depression20 21 are at a higher risk of having depression. The results have laid a strong basis for early identification and intervention.…”

Section: Introductionmentioning

confidence: 99%

A prediction algorithm for first onset of major depression in the general population: development and validation

Wang

Sareen

Patten

et al. 2014

J Epidemiol Community Health

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Panic attacks as a risk for later psychopathology: results from a nationally representative survey

Abstract: The presence of panic attacks may be an important indicator of overall psychological distress and the risk of more severe psychopathology in the future.

Cited by 41 publications

References 43 publications

Excessive Mood Elevation and Behavioral Activation with Antidepressant Treatment of Juvenile Depressive and Anxiety Disorders: A Systematic Review

Excessive Mood Elevation and Behavioral Activation with Antidepressant Treatment of Juvenile Depressive and Anxiety Disorders: A Systematic Review

Pretyphoon Panic Attack History Moderates the Relationship Between Degree of Typhoon Exposure and Posttyphoon PTSD and Depression in a Vietnamese Sample

A prediction algorithm for first onset of major depression in the general population: development and validation

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