Panic-attack-induced transient leukocytosis in a healthy male: a case report

Iskandar, Joseph W.; Griffeth, Benjamin; Sapra, Mamta; Singh, Karamjit; Giugale, Juan M.

doi:10.1016/j.genhosppsych.2011.02.004

Cited by 5 publications

(5 citation statements)

References 3 publications

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“…With regard to the hematological parameters, the most outstanding result recorded in the current study was a slight leukocytosis in the exercise group after the physical activity intervention, which can be explained because of the catecholamine-induced demarginating of white blood cells and increased release from the bone marrow storage reserve during exercise (65). AP increased in both groups after the 6 months follow-up, reflecting the rapid growing peak of the children and increased bone metabolism (66).…”

Section: Discussionmentioning

confidence: 56%

Implementation of a Physical Activity Program Protocol in Schoolchildren: Effects on the Endocrine Adipose Tissue and Cognitive Functions

et al. 2021

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Practicing exercise is one of the best strategies to promote well-being and quality of life, however physical activity in schoolchildren and adolescents is developed in an unpredictable, intermittent way and in short periods. There are relatively few intervention studies investigating the role of physical activity in schoolchildren endocrine function of adipose tissue and cognitive function. One hundred and three boys, divided into two groups: control (n = 51, did not perform additional physical activity) and exercise (n = 52, performed vigorous physical activity after the regular school classes). The exercise group, developed a 6 months physical activity protocol delivered by the physical education teacher during the second semester of the academic course (6 months). Body composition measurements, adherence to the Mediterranean diet, nutritional intake, hematological and biochemical parameters, endocrine function of the adipose tissue and biomarkers of brain molecular function were assessed at enrolment and after 6 months of intervention. No statistically significant differences between both groups were found for age, height and bone mass. Weight and BMI was lower in the exercise group compared to the control group, increasing lean mass and reducing fat mass. 58.68% of children in the exercise group showed high adherence to the Mediterranean Diet compared to 46.32% of the control group. The exercise group was more concerned about their diet consumed more fiber, vitamin B1, B2, B6, B12, D, Niacin, Folic acid, Fe, Zn, Se and Cu. Triglycerides levels and HDL-cholesterol were higher in the exercise group at the end of the study. Leptin, MCP-1, lipocalin-2, adipsin and PAI-1 levels were lower in the exercise group at the end of the exercise protocol. In contrast, adiponectin and osteocrin markedly increased in the exercise group. Moreover, marked increases were recorded in healthy brain state biomarkers (NGF, BDNF, and irisin) in the exercise group, which could have a positive impact on academic performance. Taken together, all the findings reported are consistent with many benefits of the exercise protocol on adipose tissue and brain molecular function, demonstrating the usefulness of early interventions based on physical activity in children to reduce risk factors related to sedentary lifestyle.

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Section: Discussionmentioning

confidence: 56%

Implementation of a Physical Activity Program Protocol in Schoolchildren: Effects on the Endocrine Adipose Tissue and Cognitive Functions

et al. 2021

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Section: Discussionmentioning

confidence: 99%

“…This activates the sympathetic nervous system, which impacts processes associated with the immune system, thereby affecting NLR (Kalelioglu & Karamustafalioglu, 2019). Indeed, lymphopenia (decreased lymphocyte counts) and neutrophilia (increased neutrophil counts), suggestive of a stress leukogram,, have been found to occur under conditions of acute psychological stress in humans (Abramson & Melton, 2000; Benschop et al, 1996; Iskandar et al, 2011). Although we do not have data to investigate a return to baseline NLR in the period of time following arrival to the new facility, the fact that NLR values continued to be significantly higher within 1 week of arrival suggests some continued level of stress during that time period, perhaps related to acclimation in addition to transport.…”

Section: Discussionmentioning

confidence: 99%

Neutrophil to lymphocyte ratio in captive olive baboons (Papio anubis): The effects of age, sex, rearing, stress, and pregnancy

Neal,

Achorn,

Schapiro

et al. 2024

American J Primatol

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In apes and humans, neutrophil to lymphocyte ratio (NLR) can be used as a predictive indicator of a variety of clinical conditions, longevity, and physiological stress. In chimpanzees specifically, NLR systematically varies with age, rearing, sex, and premature death, indicating that NLR may be a useful diagnostic tool in assessing primate health. To date, just one very recent study has investigated NLR in old world monkeys and found lower NLR in males and nursery‐reared individuals, as well as a negative relationship between NLR and disease outcomes. Given that baboons are increasingly used as research models, we aimed to characterize NLR in baboons by providing descriptive data and examinations of baboon NLR heritability, and of the relationships between NLR, age, rearing, and sex in 387 olive baboons (Papio anubis) between 6 months and 19 years of age. We found that (1) mother‐reared baboons had higher NLRs than nursery‐reared baboons; (2) females had higher NLRs than males; and (3) there was a quadratic relationship between NLR and age, such that middle‐aged individuals had the highest NLR values. We also examined NLR as a function of transport to a new facility using a subset of the data. Baboons exhibited significantly higher transport NLRs compared to routine exam NLRs. More specifically, adult baboons had higher transport NLRs than routine NLRs, whereas juveniles showed no such difference, suggesting that younger animals may experience transport stress differently than older animals. We also found that transport NLR was heritable, whereas routine NLR was not, possibly suggesting that stress responses (as indicated in NLR) have a strong genetic component. Consistent with research in humans and chimpanzees, these findings suggest that NLR varies with important biological and life history variables and that NLR may be a useful health biomarker in baboons.

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“…The bone marrow increases the production of WBCs in response to inflammation, infection, and physical and mental stress. Stress can cause the release of WBCs stored in the bone marrow, which could present as reactive leukocytosis [ 2 ]. Routine medications, such as corticosteroids, lithium, and beta-agonists, cause leukocytosis as well.…”

Section: Introductionmentioning

confidence: 99%

Post-cardiac Arrest Leukocytosis Mimicking Acute Monocytic Leukemia

Kahlon¹,

Doddi²,

Abuhelwa³

et al. 2022

Cureus

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Leukocytosis is defined by an increased WBC count in the peripheral blood. This can be caused by many pathologies from benign conditions such as stress, infection, and inflammation or malignant origins such as leukemia. Although leukocytosis is regularly encountered clinically and has many etiologies making a definitive diagnosis, at times, may be difficult. A case of severe leukocytosis requires careful consideration of symptoms and confirmation with serial complete blood count (CBC) testing before pursuing further invasive testing such as bone marrow biopsy. Here, we report the case of a 78-year-old male patient who, after a cardiac arrest, presented with reactive hyperleukocytosis mimicking acute monocytic leukemia.

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Panic-attack-induced transient leukocytosis in a healthy male: a case report

Cited by 5 publications

References 3 publications

Implementation of a Physical Activity Program Protocol in Schoolchildren: Effects on the Endocrine Adipose Tissue and Cognitive Functions

Implementation of a Physical Activity Program Protocol in Schoolchildren: Effects on the Endocrine Adipose Tissue and Cognitive Functions

Neutrophil to lymphocyte ratio in captive olive baboons (Papio anubis): The effects of age, sex, rearing, stress, and pregnancy

Post-cardiac Arrest Leukocytosis Mimicking Acute Monocytic Leukemia

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