Pangenome-based design of strain-specific primers allows the specific monitoring of engraftment in different habitats
Sarah Lebeer,
Tom Eilers,
Lize Delanghe
et al.
Abstract:Lactic acid bacteria (LAB), including many well-known beneficial bacteria, have seen a rise in the number of applications with specific strains across various areas, including live biotherapeutic products (LBPs). The most extensively researched strains belong to the Lactobacillaceae. Assessing the survival and persistence of specific strains in different niches is still an important challenge, while selective monitoring techniques are often lacking at strain level. Here, we show a robust pangenome-based approa… Show more
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