“…Adverse reactions to colloidal starch are infrequent (Mishler et al, found 40 in 566,755 infusions or 0.007%) and are typically transient, mild, and clinically insignificant [9]. However, occasional "lifethreatening reactions do occur (Mishler et al, found three in 566,755 infusions or <O.OO 1 %), but the association of such serious reactions with the starch infusion is sometimes in question [9,10]. Rarely, severe pruritis has been reported that occurs 2-3 weeks following the infusion of several liters of HES within approximately 1 week.…”