PandemicVibrio parahaemolyticuswave succession by gene loss
Chao Yang,
Hongling Qiu,
Sarah L. Svensson
et al.
Abstract:While the importance of spontaneous mutation and gene acquisition in the emergence and adaptive evolution of microbial pathogens is well recognized, the role of gene loss remains underexplored. Here, by large-scale phylogenomic analysis of 8,684 global isolates, we reconstructed the origin and evolutionary dynamics of the pandemic clone (PC) ofVibrio parahaemolyticus, the leading cause of seafood-associated infections worldwide. As has also been observed for the pandemic lineage ofV. cholerae, there was an ‘ex… Show more
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