Pandemic H1N1 illness prognosis: evidence from clinical and epidemiological data from the first pandemic wave in São Paulo, Brazil

Bellei, Nancy; Cabeça, Tatiane Karen; Carraro, Emerson; Goto, Janaína Midori; Cuba, Gabriel Trova; Hidalgo, Sônia Regina; Burattini, Marcelo Nascimento

doi:10.6061/clinics/2013(06)19

Cited by 3 publications

(1 citation statement)

References 18 publications

(13 reference statements)

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“…Srinivasa et al, 15 reported that common age group that suffered with H1N1infection was 21-30 years (60%) followed by 31-40 (30%). Bellei et al, 16 also confirmed the great burden of 2009 pandemic H1N1 infection among young adults.…”

Section: Discussionmentioning

confidence: 87%

Review of swine flu positive cases in Kakinada-2018

Pradeepika¹,

Mathangi²,

Chakravarthi³

et al. 2020

IJIRM

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Influenza is known to cause annual seasonal epidemics. Swine origin influenza was first recognized in the border area of Mexico and United States in April 2009. 1 The currently circulating strain of Swine origin influenza virus of the H1N1 strain has undergone triple re-assortment and contains genes from the avian, swine and human viruses and is known for the rapidity with which it spreads to the community. 2 Materials and Methods: 400 cases suspected with influenza like illness from in and out patient units of department of Pulmonary Medicine, Government General Hospital, Kakinada were included in the study. 70 patients were subjected to RT-PCR. Medical records of 42 patients who were admitted, who were suspected clinically as H 1 N 1 and confirmed by RT-PCR method, were examined thoroughly in the present study. An ethical committee approval and consent was taken from all patients before included in the study. Results: out of 400 cases 250 are of category A and 80 patients are of category B. Out of Category C patients, 42 are H1N1 positive by RT-PCR. Among 42 cases, most common affected age group is 51-60 years (37.40%). Males are more involved (52.38%). The common presenting symptoms were breathlessness, cough, and fever. 59.52% of positive cases were associated with various comorbidities. Conclusions: Most of patients with influenza like illness belongs category A and B. In our area H1N1 prevalence of is high in elderly age group and in males. Most of the patients recovered well with Oseltamivir and symptomatic treatment. Proper preventive measures, personal care and hygiene and isolation of patients and admission to designated swine flu ward can be helpful in preventing the spread of infection with in the community.

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Section: Discussionmentioning

confidence: 87%

Review of swine flu positive cases in Kakinada-2018

Pradeepika¹,

Mathangi²,

Chakravarthi³

et al. 2020

IJIRM

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Safety and effectiveness of neuraminidase inhibitors in situations of pandemic and/or novel/variant influenza: a systematic review of the literature, 2009–15

Boikos

Caya

Doll

et al. 2017

Journal of Antimicrobial Chemotherapy

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Most included studies were observational, statistically underpowered and at high risk of reporting biased and/or confounded effect estimates. NI treatment appeared likely effective in reducing mortality (cause unspecified) and pneumonia in general populations, with increasing benefit when administered with 48 h of symptom onset. NI pre- or post-exposure prophylaxis is likely effective in reducing secondary transmission of influenza in a general population. Our evidence suggests NIs are likely safe to use in the general population; however, data for children and pregnant women are limited. Knowledge gaps persist in specific populations such as Aboriginals, high-risk individuals and the elderly.

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Laboratory-confirmed deaths caused by influenza A (H1N1)pdm09 in the Santa Catarina State, Brazil, 2009-2014

Pereira

Kupek

2016

Rev. Soc. Bras. Med. Trop.

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Introduction: Little information is available on the evolution of infl uenza A (H1N1)pdm09-related mortality in Brazil. Methods: During the period 2009-2014, offi cial epidemiological surveillance and mortality data were used to ascertain infl uenza-related deaths in the Santa Catarina State in Brazil. Results: The highest overall mortality rate (2.3 per 100,000) was observed in 2009. Pregnant women constituted the highest risk group (mortality rate 18.0 per 100,000). Following vaccination of high-risk groups, the rate reduced sharply but peaked again in 2012. It subsequently decreased, albeit more gradually. Conclusions: Infl uenza A (H1N1)pdm09 mortality demonstrated a cyclic pattern, with two peaks followed by a gradual decrease.

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Pandemic H1N1 illness prognosis: evidence from clinical and epidemiological data from the first pandemic wave in São Paulo, Brazil

Cited by 3 publications

References 18 publications

Review of swine flu positive cases in Kakinada-2018

Review of swine flu positive cases in Kakinada-2018

Safety and effectiveness of neuraminidase inhibitors in situations of pandemic and/or novel/variant influenza: a systematic review of the literature, 2009–15

Laboratory-confirmed deaths caused by influenza A (H1N1)pdm09 in the Santa Catarina State, Brazil, 2009-2014

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