Pandemic A/H1N1/2009 influenza in a paediatric haematology and oncology unit: successful management of a sudden outbreak

Buchbinder, Nimrod; Dumesnil, C.; Pinquier, Didier; Merle, V.; Filhon, Bruno; Schneider, Pascale; Vannier, Jean‐Pierre

doi:10.1016/j.jhin.2011.04.019

Cited by 29 publications

(24 citation statements)

References 24 publications

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“…Influenza is easily transmitted within the health care setting. Investigations of outbreaks that occurred in pediatric oncology units have identified infected visitors [11] and infected health care workers [12,13] as common sources of infection. These observations highlight the importance of universal influenza vaccination of health care workers as well as enforcement of appropriate use of sick leave.…”

Section: Transmissionmentioning

confidence: 99%

“…These observations highlight the importance of universal influenza vaccination of health care workers as well as enforcement of appropriate use of sick leave. Multiple reports have also described the role that group activities have played in propagation of influenza outbreaks on pediatric oncology units [11,12]. Providing protection for patients is complex because infected individuals may be difficult to identify and transmission can occur from asymptomatic individuals.…”

Section: Transmissionmentioning

confidence: 99%

“…One study described an influenza outbreak (n ϭ 6) in a pediatric oncology unit with successful chemoprophylaxis of all exposed hospitalized patients [11]. Oseltamivir treatment was instituted in addition to isolation of infected patients, use of protective equipment, and visitor restriction.…”

Section: Primary Chemoprophylaxismentioning

confidence: 99%

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Protecting Pediatric Oncology Patients From Influenza

et al. 2013

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Influenza is a common respiratory pathogen. Its severity can be unpredictable, but people with chronic illness are at increased risk of severe infection, complications, and death from influenza. This review examines evidence to support various strategies to protect pediatric oncology patients from influenza-related morbidity. Influenza vaccination should be considered standard. Additional evidence-supported measures include antiviral treatment, antiviral prophylaxis, cohorting of patients, and hospital infection control measures. Data from other high-risk populations support the vaccination of family members, double-dose or high-dose vaccination, and the use of barrier methods. These measures have the potential to optimize patient outcomes because there will be fewer treatment interruptions for acute illness. These strategies can also protect patients from prolonged hospitalizations and morbidity related to influenza. The Oncologist 2013;18:204 -211 Implications for Practice: Pediatric oncology patients can have very severe infections with the influenza virus. Their vulnerability is due to chronic illness and immune suppression. Simple strategies, such as ensuring vaccination, infection control measures, and education regarding personal protection can protect this population that is susceptible to severe influenza.

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Section: Transmissionmentioning

confidence: 99%

Section: Transmissionmentioning

confidence: 99%

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Protecting Pediatric Oncology Patients From Influenza

et al. 2013

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“…While comprehensive data on the testing of caregiving relatives and HCW is lacking, studies have been published on influenza transmission on pediatric wards [19,20]. A prospective study conducted by Melchior et al [19] in the influenza pandemic 2009, 2010, and 2011 in Brazil, confirmed that asymptomatic influenza infections in HCW and caregivers constitute an issue worthy of consideration in daily routines: Influenza (A, A(H1N1), A nontyped, and B) was detected in 8% of asymptomatic HCW, and 28% of asymptomatic caregivers.…”

Section: Discussionmentioning

confidence: 99%

“…Among the vaccinated group, 2.9% and 11.8% tested positive for an influenza subtype contained in the vaccine, respectively [19]. Buchbinder et al [20] reported on an influenza A(H1N1) outbreak on a pediatric ward, where the source was probably a visiting family member or an asymptomatic HCW. The outbreak led to substantial morbidity in the affected patients.…”

Section: Discussionmentioning

confidence: 99%

Case Report on the Prevention of an Endemic Outbreak of Influenza B on an Allogeneic Transplant Ward

Heidrich

Boldt²,

Stölzel³

et al. 2016

J Leuk

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Respiratory tract infections pose a threat to hematopoietic stem cell recipients, increasing morbidity and mortality rates. To address this, preventive measures are of great importance. We describe the early detection of influenza B in a patient who received a recent hematopoietic transplantation, and elucidation of the transmission path using a point-of-care multiplex polymerase chain reaction panel, leading to prevention of viral spread. The use of risk-score systems and point-of-care testing should be further evaluated.

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