Pandemi Döneminde Ayırıcı Tanının Önemi: COVID-19, Bruselloz ve Kırım-Kongo Kanamalı Ateşi Birlikteliği Olan Bir Olgu Sunumu

Gül, Özlem; Binay, Umut Devrim; Barkay, Orçun; Karakeçili, Faruk

doi:10.5578/mb.20229815

Cited by 2 publications

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“…The coronavirus disease-2019 (COVID-19) that has affected millions of people worldwide has been effective in our country since March 2020. The common symptoms observed in COVID-19 patients are highly similar to the symptoms in patients with Crimean-Congo Hemorrhagic Fever (CCHF) (1). There have also been cases of mixed infections of CCHF and COVID-19 during the COVID-19 pandemic (2).…”

Section: Introductionmentioning

confidence: 75%

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An evaluation of the laboratory and clinical data of the Crimean-Congo hemorrhagic fever patients during the Covid-19 pandemic

ÖNER¹,

ÖZGÜLER²

2023

J Exp Clin Med

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In this study, the purpose was to investigate the demographic, laboratory, and clinical characteristics of the Crimean-Congo Hemorrhagic Fever (CCHF) cases that were treated in our hospital during the Coronavirus disease-2019 (COVID-19) pandemic. It was also investigated whether the patients hospitalized with a provisional diagnosis of CCHF who tested negative for CCHF PCR were infected with COVID-19. In our study, data (epidemiological, clinical, laboratory, prognosis) from 38 patients diagnosed with CCHF through reverse-transcriptase polymerase chain reaction (PCR) and viral-RNA and/or Immunoglobulin M antibodies using ELISA between May 2020 and November 2022 were investigated retrospectively. Of all the patients, 23 were CCHF PCR (+) and 15 were CCHF PCR (-).15 (65.2%) of PCR (+) patients and 9 (60%) of PCR (-) patients were engaged in farming. 65.2% of PCR (+) and 26.7% of PCR (-) patients presented with a history of tick bites. 21 (91.3%) of PCR (+) and 12 (80%) of PCR (-) patients had a history of rural living. Among the PCR (+) patients, 65.2%, 17.4%, and 17.4% received treatment for CCHF in 2022, 2021, and 2020 respectively. 87% of PCR (+) and 60% of PCR (-) patients were discharged after full recovery. The most common symptoms were fever, diffuse body ache, weakness, and headache. Significant differences were found between PCR (+) and PCR (-) patients in terms of leukocytes, LDH, INR, NEU, PLT, fibrinogen, and NLR values. 3 patients hospitalized with a provisional diagnosis of CCHF tested negative for CCHF PCR and positive for COVID-19 PCR. Thoracic CT, clinical, and laboratory findings of these patients showed no differences from the other patients. The possibility of misdiagnosis should be considered in CCHF and COVID-19 infections due to their similar symptoms and indications. Extensive multicentric studies need to be conducted to investigate the causes of the increased number of CCHF cases during the pandemic.

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Section: Introductionmentioning

confidence: 75%

“…CCHF is an important public health issue in Türkiye due to high mortality rates (1). CCHF can be seen in people of any age and sex.…”

Section: Discussionmentioning

confidence: 99%

An evaluation of the laboratory and clinical data of the Crimean-Congo hemorrhagic fever patients during the Covid-19 pandemic

ÖNER¹,

ÖZGÜLER²

2023

J Exp Clin Med

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Optimal diagnostic fever thresholds using non-contact infrared thermometers under COVID-19

Fan

Liu

et al. 2022

Front. Public Health

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Fever screening is an effective method to detect infectors associated with different variants of coronavirus disease 2019 (COVID-19) based on the fact that most infectors with COVID-19 have fever symptoms. Non-contact infrared thermometers (NCITs) are widely used in fever screening. Nevertheless, authoritative data is lacking in defining “fever” at different body surface sites when using NCITs. The purpose of this study was to determine the optimal diagnostic threshold for fever screening using NICTs at different body surface sites, to improve the accuracy of fever screening and provide theoretical reference for healthcare policy. Participants (n = 1860) who were outpatients or emergency patients at Chengdu Women's and Children's Central Hospital were recruited for this prospective investigation from March 1 to June 30, 2021. NCITs and mercury axillary thermometers were used to measure neck, temple, forehead and wrist temperatures of all participants. Receiver operating characteristic curves were used to reflect the accuracy of NCITs. Linear correlation analysis was used to show the effect of age on body temperature. Multilinear regression analysis was used to explore the association between non-febrile participant's covariates and neck temperature. The mean age of participants was 3.45 ± 2.85 years for children and 28.56 ± 7.25 years for adults. In addition 1,304 (70.1%) participants were children (≤12), and 683 (36.7%) were male. The neck temperature exhibited the highest accuracy among the four sites. Further the optimal fever diagnostic thresholds of NCITs at the four body surface measurement sites were neck (36.75 °C, sensitivity: 0.993, specificity: 0.858); temple (36.55 °C, sensitivity: 0.974, specificity: 0.874); forehead (36.45 °C, sensitivity: 0.961, specificity: 0.813); and wrist (36.15 °C, sensitivity: 0.951, specificity: 0.434). Based on the findings of our study, we recommend 36.15, 36.45, 36.55, and 36.75 °C as the diagnostic thresholds of fever at the wrist, forehead, temple and neck, respectively. Among the four surface sites, neck temperature exhibited the highest accuracy.

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Pandemi Döneminde Ayırıcı Tanının Önemi: COVID-19, Bruselloz ve Kırım-Kongo Kanamalı Ateşi Birlikteliği Olan Bir Olgu Sunumu

Cited by 2 publications

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An evaluation of the laboratory and clinical data of the Crimean-Congo hemorrhagic fever patients during the Covid-19 pandemic

An evaluation of the laboratory and clinical data of the Crimean-Congo hemorrhagic fever patients during the Covid-19 pandemic

Optimal diagnostic fever thresholds using non-contact infrared thermometers under COVID-19

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