Pancytopenia as a Presentation of Iron Deficiency: A Case Report

Abstract

One of the most common nutritional deficiencies worldwide is iron deficiency. Fatigue, pallor, vertigo, dyspnea, cold intolerance, lethargy, palpitation, headache, and the pallor of the mucous membranes or nail beds are the most frequent symptoms and signs of iron deficiency. Thrombocytosis is commonly observed in iron deficiency anemia; it seems that erythropoietin plays the main role in this respect. Furthermore, thrombocytopenia and even leukopenia have been reported in iron deficiency; however, pancytopenia is a very rare condition. In this report, we presented two unusual cases of pancytopenia due to severe iron deficiency that improved after treatment with oral iron supplements. Iron deficiency anemia, if sufficiently severe, may be associated with reduced platelet and leukocyte counts. Accordingly, this condition should be considered as a differential diagnosis in all patients with pancytopenia.

Iron Deficiency Anemia Presenting With Pancytopenia: A Study From India

“…DAT was negative and Hb electrophoresis was normal; however, both patients’ serum ferritin was decreased (Case 1: 0.9 ng/mL; Case 2: 2 ng/mL). Other iron profile parameters also favored IDA and patients responded well with oral iron [ 20 ]. In another case report, a seven-year-old male child presented with pancytopenia and was diagnosed as IDA, without other causes of pancytopenia or any other malignant disease.…”

An atypical presentation of endometrial cancer as angina secondary to critically low hemoglobin and iron deficiency associated pancytopenia: A case report

“…Unfortunately, recent international surveys indicate there are still many barriers to women seeking investigation and treatment for AUB, and many women do not seek care [ 5 ]. While it is relatively common for women with AUB to suffer with iron deficiency anemia [ 4 ], pancytopenia secondary to iron deficiency is extremely rare, with only a handful of case reports in the literature [ [6] , [7] , [8] ].…”