Pancreatoscopy-guided electrohydraulic lithotripsy for the treatment of obstructive pancreatic duct stones: a prospective consecutive case series

Wiel, Sophia E. van der; Stassen, Pauline M.; Jong, David M. de; Poley, Jan–Werner; Jonge, P.J.F. de; Bruno, Marco J.

doi:10.1016/j.gie.2021.11.047

Cited by 19 publications

(12 citation statements)

References 25 publications

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“…Most of the included studies, however, were in nature retrospective and used pancreatoscopy-guided lithotripsy as secondary treatment after failure of ESWL. Therefore, we have prospectively evaluated the technical and clinical success of per-oral pancreatoscopy-guided EHL as first-line treatment in a consecutive series of patients 8 . In this study, a total of 34 patients were included of whom 25 underwent EHL, which was followed by complete or partial stone clearance in 24 patients.…”

Section: Discussionmentioning

confidence: 99%

Section: Study Design and Populationmentioning

confidence: 99%

“…For the EHL cohort, we included patients who were technically successful treated with pancreatoscopy-guided EHL as first-line treatment and who participated in the previous PEL-STONE study [8]. The EHL technique and protocol we used have been described in detail previously [8]. In short, in all patients a pancreatic sphincterotomy was performed to facilitate introduction of the pancreatoscope (SpyGlass DS Direct Visualization System, Boston Scientific Corp, Natick, Massachusetts, United States).…”

Section: Study Design and Populationmentioning

confidence: 99%

“…With pancreatoscopy-guided intraductal electrohydraulic lithotripsy (EHL), fragmentation of stones is achieved under direct visualization by the absorption of shockwave pulses generated by a bipolar probe in an aqueous medium [7]. We recently evaluated the efficacy and safety of pancreatoscopyguided EHL as first-line therapy in consecutive patients with obstructive chronic calcifying pancreatitis (PELSTONE study) [8]. When PD cannulation was achieved, pancreatoscopy was technically successful in 92 % of patients defined as complete (100 %) or partial ductal clearance (50 % to 99 %) based on post-EHL pancreatoscopic imaging and fluoroscopic pancreatogram.…”

Section: Introductionmentioning

confidence: 99%

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Long-term outcomes of pancreatoscopy-guided electrohydraulic lithotripsy for the treatment of obstructive pancreatic duct stones

et al. 2023

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Background and study aims Pancreatoscopy-guided electrohydraulic lithotripsy (EHL) has proven to be an effective first-line therapy in symptomatic chronic pancreatitis (CP) patients with obstructing pancreatic duct (PD) stones 1. However, long-term outcomes of endoscopic EHL remain unknown. The aim of the present study was to evaluate the long-term treatment effects of EHL as first-line therapy and to compare with those obtained in a historical cohort of patients who underwent extracorporeal shockwave lithotripsy (ESWL) as primary treatment. Patients and methods An observational retrospective single-center long-term follow-up study was performed including 19 consecutive patients who previously underwent endoscopic EHL compared to 18 patients who underwent ESWL followed by endoscopic retrograde pancreatography (ERP). The primary endpoint was long-term treatment success after EHL or ESWL defined as no recurrence of symptomatic intraductal stones confirmed on imaging. Secondary endpoints for the EHL-population included long-term clinical success (i. e., a similar or lower Izbicki Pain Score or reduction in opiate usage as compared to 6-month follow-up), quality of life (QoL), pancreatic function and hospital re-admission rate. Results In the EHL group, 37 % of the patients developed recurrent symptomatic PD stones versus 61 % in the ESWL group after a median follow-up of 35.0 and 76.5 months. Of the patients with recurrence, 71 % versus 100 % underwent a reintervention. Median time to recurrence was 12.0 versus 13.0 months. Clinical success sustained in 58 % of the EHL patients. QoL was not significantly different compared with 6-month follow-up and baseline. Conclusions Also at long-term follow-up, endoscopic EHL as first-line treatment is moderately effective for symptomatic CP patients with treatment success rates that seems at least equally effective as ESWL.

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Section: Discussionmentioning

confidence: 99%

Section: Study Design and Populationmentioning

confidence: 99%

Section: Study Design and Populationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Long-term outcomes of pancreatoscopy-guided electrohydraulic lithotripsy for the treatment of obstructive pancreatic duct stones

et al. 2023

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“…The use of peroral pancreatoscopy (POPS) and electrohydraulic lithotripsy (EHL) to treat endoscopic pancreatic stones has recently been reported as an effective treatment 1 . Here, we report a case of successful removal of pancreatic stones with POPS (SpyScopeDII; Boston Scientific, Marlborough, Massachusetts, USA) and EHL using single-balloon-assisted endoscopy (BAE) in a patient with surgically altered anatomy.…”

Section: Figmentioning

confidence: 99%

Single-balloon-assisted endoscopy with peroral pancreatoscopy and electrohydraulic lithotripsy

et al. 2022

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Utility of an innovative basket catheter for endoscopic removal of fragmented or small pancreatic stones

Kato,

Yoshida,

Kataoka

2024

J Hepato Biliary Pancreat

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Pancreatoscopy-guided electrohydraulic lithotripsy for the treatment of obstructive pancreatic duct stones: a prospective consecutive case series

Cited by 19 publications

References 25 publications

Long-term outcomes of pancreatoscopy-guided electrohydraulic lithotripsy for the treatment of obstructive pancreatic duct stones

Long-term outcomes of pancreatoscopy-guided electrohydraulic lithotripsy for the treatment of obstructive pancreatic duct stones

Single-balloon-assisted endoscopy with peroral pancreatoscopy and electrohydraulic lithotripsy

Utility of an innovative basket catheter for endoscopic removal of fragmented or small pancreatic stones

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