Pancreatitis in Children

Sathiyasekaran, Malathi; Biradar, Vishnu; Ganesh, Ramaswamy; Srinivas, S.; Ashish, B; Sumathi, B; Dheivamani, Nirmala; Geetha, M

doi:10.1007/s12098-016-2115-1

Cited by 18 publications

(16 citation statements)

References 30 publications

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“…Pancreatitis exhibits a wide clinical spectrum in children and may present as AP, ARP or CP (8). AP is the most common pathological entity affecting the pancreas in children, and the diagnosis of AP is based on a combination of clinical findings, biochemical tests and imaging studies (10, 12) The two classical symptoms of AP are abdominal pain and nausea/vomiting.…”

Section: Discussionmentioning

confidence: 99%

“…It is well documented that mutations in the PRSS1, CFTR and SPINK1 genes can cause hereditary pancreatitis. However, there is no clear distinction between those diseases that cause recurrent attacks of AP and those causing CP (8). An evaluation of PRSS1, SPINK1 and CFTR mutations may be beneficial in children with a family history of ARP or CP.…”

Section: Discussionmentioning

confidence: 99%

“…The common causes of AP in children include infections, abdominal trauma, drug induced injury, cholelithiasis, structural anomalies of the biliary/pancreatic junction and metabolic and systemic diseases, as well as idiopathic causes (8). The clinical manifestations can differ depending on the age of the child and the underlying etiology.…”

Section: Introductionmentioning

confidence: 99%

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Diagnosis and Management of Pancreatitis in Childhood: A Single-Centre Experience

Appak¹,

Karakoyun²,

Cetin³

et al. 2018

Iran J Pediatr

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Background: Pancreatitis can be seen at any age in childhood. Therefore, it is important for pediatricians to know the diagnosis and the management of pancreatitis. Objectives: The aim of this study was to evaluate the etiological factors, clinical features and management of pancreatitis in children. Methods: This study included hospitalized children who were diagnosed with pancreatitis. The clinical presentations, laboratory analyses, radiological features, etiologies and treatments were recorded. Results: A total of 59 pancreatic attacks were recorded in 41 patients. The most common symptoms were abdominal pain and vomiting, and the most common etiological cause was idiopathic. Approximately 22% of the patients had acute recurrent episodes. Somatostatin was used to treat 61% of the attacks; however, it did not reduce the time to recovery after an attack when compared to those patients who did not use somatostatin (P = 0.36). The white blood cell counts and urea and calcium levels were significantly different between those patients who did and did not use somatostatin. Seventeen (28.8%) of the pancreatitis attacks were determined to be severe. Moreover, a mutation in the cystic fibrosis transmembrane conductance regulator was detected in two patients with recurrent pancreatitis. Conclusions: Fever and irritability can be signs of pancreatitis in infants and toddlers. In our cases, the somatostatin treatment was not effective in terms of the time to recovery after an attack.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Diagnosis and Management of Pancreatitis in Childhood: A Single-Centre Experience

Appak¹,

Karakoyun²,

Cetin³

et al. 2018

Iran J Pediatr

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“…Hallazgos imagenológicos compatibles con pancreatitis aguda. 2,3 La incidencia de la pancreatitis aguda en la población pediátrica ha ido en aumento en Estados Unidos y es de 3,6-13,2 casos por 100 000 niños por año. 4,5 Son varias las causas de pancreatitis en niños; entre las de mayor frecuencia, se encuentran enfermedades sistémicas, como sepsis, shock, enfermedad inflamatoria intestinal, síndrome urémico hemolítico (10-50%); medicamentos, como ácido valproico, 6-mercaptopurina/azatioprina, l-asparaginasa, masalamina, trimetoprimasulfametoxazol, furosemida, tacrolimus, esteroides (5-25%); factores obstructivos: cálculos biliares, páncreas divisum, quistes en el colédoco, disfunción del esfínter de Oddi, páncreas anular (10-30%); trauma (10-20%); infección viral (8-10%); enfermedades metabólicas, como cetoacidosis diabética, hipertrigliceridemia, errores innatos del metabolismo e hipercalcemia (5-10%); y, finalmente, causas idiopáticas (15-30%).…”

Section: Niveles De Amilasa O Lipasa Tres Vecesunclassified

Pancreatitis aguda secundaria a un trauma abdominal: reporte de caso de una niña de 7 años

Montoya-Sánchez

Pereira-Ospina

Pinzón-Salamanca

et al. 2018

Arch Argent Pediatr

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Presentación de casos clínicos RESUMENLa pancreatitis consiste en la inflamación aguda del páncreas, que se caracteriza, clínicamente, por dolor abdominal. Para realizar el diagnóstico, es necesario que se presente la elevación de marcadores bioquímicos, como amilasa o lipasa pancreáticas. Esta afección es la enfermedad pancreática más frecuente tanto en niños como en adultos. Su presentación en la población pediátrica está en aumento y tiene varias etiologías, como infecciones, trauma, intoxicación y enfermedades metabólicas. Entre los mecanismos de trauma, se han descrito maltrato infantil, caídas, trauma con el manubrio de la bicicleta y accidentes de tránsito. En este artículo, se presenta un caso de pancreatitis secundaria a un trauma abdominal con el manubrio de una bicicleta en una paciente de 7 años. Palabras clave: niño, pancreatitis aguda, trauma, pancreatitis, traumatismos abdominales. ABSTRACTPancreatitis consists in acute inflammation of the pancreas that is clinically characterized by abdominal pain. To make the diagnosis it is necessary the elevation of biochemical markers like pancreatic amylase or lipase. It is the most frequent pancreatic disease in both children and adults. Its presentation in the pediatric population is increasing and has several etiologies such as: infections, trauma, intoxication and metabolic diseases. Trauma mechanisms have been described: child maltreatment, falls, trauma with the bicycle handle and traffic accidents. In this article, we present a case of pancreatitis secondary to an abdominal trauma with the handle of a bicycle in a patient of 7 years.

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“…The article on BPancreatitis in children^addresses the entire spectrum of pancreatitis i.e., acute pancreatitis (AP), acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) [8]. It will help the reader in differentiation of various forms of pancreatitis, finding the etiology and providing state of the art management.…”

mentioning

confidence: 99%

Editorial: Striving for Excellence in Pediatric Gastroenterology Care — A Continuous Effort

Srivastava

Gupte

2016

Indian J Pediatr

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Pancreatitis in Children

Cited by 18 publications

References 30 publications

Diagnosis and Management of Pancreatitis in Childhood: A Single-Centre Experience

Diagnosis and Management of Pancreatitis in Childhood: A Single-Centre Experience

Pancreatitis aguda secundaria a un trauma abdominal: reporte de caso de una niña de 7 años

Editorial: Striving for Excellence in Pediatric Gastroenterology Care — A Continuous Effort

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