Pancreatitis and typhoid fever

Hearne, Steve E.; Whigham, Thomas E.; Brady, Charles E.

doi:10.1016/0002-9343(89)90349-5

Cited by 20 publications

(12 citation statements)

References 12 publications

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“…Typhoid pancreatitis could represent the effect of the direct pancreatic localisation of bacteria which could happen by haematogenous route, lymphatic route and transmural migration, via the biliary duct system and from the duodenum via the main pancreatic duct. This may occur, especially in patients with predisposing conditions to biliary stasis, such as cholelithiasis, choledocholithiasis, and biliary duct abnormalities 13 , but our patient had no such predisposing conditions. The mechanisms may also be toxin induced or immune mediated pancreatitis 14,15 .…”

Section: Discussionmentioning

confidence: 64%

Mysterious Looks of Typhoid Fever: A New Experience

Basak

Gomes

Ahmed

et al. 2015

Bangladesh Crit Care J

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Enteric fever (typhoid or paratyphoid) is a common infectious disease worldwide, especially in developing countries like Bangladesh. Typhoid fever caused by the gram negative bacterium Salmonella typhi that may have a wide spectrum of clinical presentations. We report a case of a 17 year old previously healthy college boy who presented with fever, abdominal pain and shortness of breath later on who was eventually diagnosed as having typhoid fever complicated by acute pancreatitis, hepatitis and severe pulmonary hypertension. Enteric fever presenting as acute pancreatitis and pulmonary hypertension is a rare entity and must be considered in endemic areas like Bangladesh, in patients presenting with fever and concomitant severe abdominal pain and shortness of breath, as any delay in timely institution of treatment can prove fatal. There are very few case reports in the world which have depicted this unusual association.Bangladesh Crit Care J March 2015; 3 (1): 36-38

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Section: Discussionmentioning

confidence: 64%

Mysterious Looks of Typhoid Fever: A New Experience

Basak

Gomes

Ahmed

et al. 2015

Bangladesh Crit Care J

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show abstract

“…Typhoid pancreatitis could represent the effect of the direct pancreatic localisation of bacteria which could happen by haematogenous route, lymphatic route and transmural migration, via the biliary duct system and from the duodenum via the main pancreatic duct. This may occur, especially in patients with predisposing conditions to biliary stasis, such as cholelithiasis, choledocholithiasis, and biliary duct abnormalities [11], but our patient had no such predisposing conditions. The mechanisms may also be toxin induced or immune mediated pancreatitis [12,13].…”

Section: Discussionmentioning

confidence: 64%

Enteric Fever Presenting as Acute Pancreatitis

Chakrabarti¹,

Pan²

2014

JCR

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Abstract:Enteric fever (or typhoid) is a common infectious disease worldwide, especially in developing countries like India. We report a case of a 27 year old patient who presented with fever and abdominal pain and was eventually diagnosed as having enteric fever complicated by acute pancreatitis. Enteric fever presenting as acute pancreatitis is a rare entity and must be considered in endemic areas like India, in patients presenting with fever and concomitant severe abdominal pain as any delay in timely institution of treatment can prove fatal. There are very few case reports in the world which have depicted this unusual association.

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“…Asymptomatic typhoid pancreatitis is not significant in the prognosis. [10][11][12] The mechanism of asymptomatic pancreatitis was unclear. The 'bile reflux theory' suggests that S. typhi invades the bile and is refluxed into the pancreatic duct.…”

Section: Discussionmentioning

confidence: 99%

“…The 'bile reflux theory' suggests that S. typhi invades the bile and is refluxed into the pancreatic duct. 11 However, other causes, such as toxins or an immune response to bacteria, should also be considered. 12,13 Bulter et al 19 suggested that laboratory abnormalities compatible with DIC were common in patients with typhoid fever.…”

Section: Discussionmentioning

confidence: 99%