“…Serious complications include septic shock, systemic lipolysis, hemorrhage, and death. Systemic lipolysis (Weber-Christian disease) is a dreaded complication of PPVF due to release of pancreatic contents into the systemic circulation through the fistula, associated with a high mortality rate [3] , [4] , [5] . Clinically, patients present with polyarthritis, polyserositis, necrotic bone lesions, and purpuric nodules on the extremities.…”