“…Other procedures are invasive such as preoperative and intra-operative endoscopic ultrasound (EUS). However, all these methods have low sensitivities (Müller et al, 1994 The intra-operative EUS is more accurate and could improve the detection of pancreatic tumor (near 100%) (Chung JC, et al, 2006). Since 1990s EUS has been considered the reference method in Zaynab Alourfi *1 localizing insulinomas with using a high-frequency sonography probe, that can get very close to the pancreas ( Kann P 2016, McLean, A. M. and Fairclough P. D, 2005; Nesje LB, et al, 2002).…”