Pancreatic Pseudocyst Located in the Liver

Mofredj, Ali; Jf, Cadranel; M, Dautreaux; Kazerouni, F.; Hadj-Nacer, K; Deplaix, P; François, Geneviève; Danon, Olivier; Lukumbo, S; Collot, G; Lévy, P; Harry, G

doi:10.1097/00004836-200001000-00016

Cited by 35 publications

(11 citation statements)

References 8 publications

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“…These are primarily single case reports and mini case series but included two relatively thorough review articles which reviewed 26 cases[6] and 23 cases[7]. Two of the cases were notable in that the IHPP formation was thought to be secondary to ectopic pancreatic tissue and not an inflammatory pancreatic process[8,9].…”

Section: Resultsmentioning

confidence: 99%

“…Although IHPP lesions may be clinically suspected in a patient based on the presentation and radiological imaging, definitive diagnosis was rarely made until analysis of the cystic fluid was performed demonstrating a high amylase content[6,7,17,20,21]. …”

Section: Resultsmentioning

confidence: 99%

“…Unlike the more commonplace peripancreatic or intrapancreatic pseudocysts, for IHPPs the most common method was percutaneous aspiration or drainage (Table 2) which provided a definitive diagnosis, and was usually well tolerated with minimal complications in these patients[6,7,23]. Simple needle aspiration alone with either US or CT guidance was performed as often as drainage (Table 2).…”

Section: Resultsmentioning

confidence: 99%

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Intrahepatic pancreatic pseudocyst: A review of the world literature

Demeusy

Hosseini

Sill

et al. 2016

WJH

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AIMTo investigate and summarize the literature regarding the diagnosis and management of intrahepatic pancreatic pseudocysts (IHPP).METHODSA literature search was performed using PubMed (MEDLINE) and Google Scholar databases, followed by a manual review of reference lists to ensure that no articles were missed. All articles, case reports, systematic reviews, letters to editors, and abstracts were analyzed and tabulated. Bivariate analyses were performed, with significance accepted at P < 0.05. Articles included were primarily in the English language, and articles in other languages were reviewed with native speakers or, if none available, were translated with electronic software when possible.RESULTSWe found 41 published articles describing 54 cases since the 1970s, with a fairly steady rate of publication. Patients were predominantly male, with a mean age of 49 years. In 42% of published cases, the IHPP was the only reported pseudocyst, but 58% also had concurrent pseudocysts in other extrapancreatic locations. Average IHPP size was 9.5 cm and they occurred most commonly (48%) in the left hemiliver. Nearly every reported case was managed with an intervention, most with a single intervention, but some required up to three interventions. Percutaneous treatment with either simple aspiration or with an indwelling drain were the most common interventions, frequently performed along with stenting of the pancreatic duct. The size of the IHPP correlated significantly with both the duration of treatment (P = 0.006) and with the number of interventions required (P = 0.031). The duration of therapy also correlated with the initial white blood cell (WBC) count (P = 0.048).CONCLUSIONDiagnosis of IHPP is difficult and often missed. Initial size and WBC are predictive of the treatment required. With appropriate intervention, most patients achieve resolution.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Intrahepatic pancreatic pseudocyst: A review of the world literature

Demeusy

Hosseini

Sill

et al. 2016

WJH

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“…Pancreatic pseudocysts can present various complications, some more common such as infection, rupture, and gastrointestinal obstruction, to the slightly rarer. Hepatic pseudocysts are a recognized but rare phenomenon described within published case reports 7 8 9 10 11 12 . In one report of a patient presenting with a large liver cystic lesion in association with a pancreatic tail pseudocyst, the authors proposed several potential mechanisms for development of hepatic pseudocysts, including through direct invasion or possibly presence of heterotopic pancreatic tissue within the liver.…”

Section: Discussionmentioning

confidence: 99%

Pancreatic pseudocyst-portal vein fistula with refractory hepatic pseudocyst: Two cases treated with EUS cyst-gastrostomy and review of the literature

et al. 2019

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Background and study aims Pseudocysts are the most common pancreatic cystic lesions and they usually develop in association with pancreatitis of at least 4 weeks’ duration. Extra-pancreatic pseudocysts, although reported, are relatively uncommon. Secondary liver pseudocysts are recognized within the literature, and most patients described have required percutaneous or surgical drainage due to infection or symptoms. The mechanism of hepatic pseudocyst formation is not entirely clear but it is postulated that this phenomenon may occur through pseudocyst-portal vein fistulization. We describe two cases of patients presenting with pancreatic pseudocysts invading the portal venous system with embolization of pancreatic fluid to the liver and subsequent hepatic pseudocyst formation. Interestingly, liver pseudocyst resolution was incomplete with antibiotics and percutaneous drainage alone, and only occurred following endoscopic ultrasonography-guided pancreatic cyst-gastrostomy and metal stent insertion. We have reviewed the current literature on the diagnosis and management of pseudocyst-portal vein fistula formation and we believe that our cases represent the first published within the literature to describe this treatment approach.

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“…Nealon and Walser [52]have proposed a simple ERCP classification of pancreatic ductal anatomy in pancreatic pseudocysts (table 2). The following are key features that we believe must be known for optimum clinical management [53, 54, 55]. (1) The underlying cause of pancreatitis and whether there has been a history of acute pancreatitis or whether there is underlying chronic pancreatitis.…”

Section: Classificationmentioning

confidence: 99%