Pancreatic Encephalopathy and Cerebral Hemorrhage in Patient With Severe Acute Pancreatitis

Minhas, Parminder; Brown, Brent

doi:10.1016/j.chest.2020.08.707

Cited by 6 publications

(3 citation statements)

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“…A syndrome of pancreatic encephalopathy in patients with acute pancreatitis can cause cerebral thrombosis and cerebral edema through phospholipase A2 toxicity, although some experts contend that thiamine deficiency plays a role in the pathogenesis of this rare and potentially fatal disorder. 63,64 Sepsis-associated Encephalopathy Sepsis-associated encephalopathy, present in 20% to 70% of patients with sepsis, is the most common cause of altered mental status in medical critical illness. 65,66 Gastrointestinal infections show the strongest association with sepsis-associated encephalopathy.…”

Section: Wernicke Encephalopathymentioning

confidence: 99%

“…Incidentally, metronidazole can cause inhibition of thiamine pyrophosphorylation, triggering Wernicke encephalopathy in patients predisposed to thiamine deficiency, and thiamine administration is a key part of management in addition to cessation of the drug. A syndrome of pancreatic encephalopathy in patients with acute pancreatitis can cause cerebral thrombosis and cerebral edema through phospholipase A2 toxicity, although some experts contend that thiamine deficiency plays a role in the pathogenesis of this rare and potentially fatal disorder 63,64 …”

Section: Encephalopathy Syndromesmentioning

confidence: 99%

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Neurologic Complications of Critical Medical Illness

Morris¹,

Sarwal²

2023

CONTINUUM: Lifelong Learning in Neurology

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Objective This article reviews the neurologic complications encountered in patients admitted to non-neurologic intensive care units, outlines various scenarios in which a neurologic consultation can add to the diagnosis or management of a critically ill patient, and provides advice on the best diagnostic approach in the evaluation of these patients. Latest Developments Increasing recognition of neurologic complications and their adverse impact on long-term outcomes has led to increased neurology involvement in non-neurologic intensive care units. The COVID-19 pandemic has highlighted the importance of having a structured clinical approach to neurologic complications of critical illness as well as the critical care management of patients with chronic neurologic disabilities. Essential Points Critical illness is often accompanied by neurologic complications. Neurologists need to be aware of the unique needs of critically ill patients, especially the nuances of the neurologic examination, challenges in diagnostic testing, and neuropharmacologic aspects of commonly used medications.

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Section: Wernicke Encephalopathymentioning

confidence: 99%

Section: Encephalopathy Syndromesmentioning

confidence: 99%

Neurologic Complications of Critical Medical Illness

Morris¹,

Sarwal²

2023

CONTINUUM: Lifelong Learning in Neurology

View full text Add to dashboard Cite

show abstract

“…A case report of subarchnoid hemorrhage is presented as an additional complication in a patient with acute severe pancreatic encephalopathy [5] The current initial management has to focus on fluid resuscitation, with some data to support Ringer's lactate over physiological saline. Prophylactic use of antibiotics is not recommended.…”

Section: Main Bodymentioning

confidence: 99%