Pancreatic ductal adenocarcinoma: preoperative assessment with helical CT versus dynamic MR imaging.

Abstract

Dynamic MR imaging may be better than helical CT in the preoperative detection and evaluation of local tumor extension and of vascular involvement of pancreatic ductal adenocarcinomas.

Preoperative evaluation of pancreatic cancer: Comparison of gadolinium‐enhanced dynamic MRI with MR cholangiopancreatography versus MDCT

“…1). This result is supported by previous reports in which the excellent ability of MR regarding tumor detection ranging 90 -100%, has been reported (11,24,26,29). This greater conspicuity could be attributed to the intrinsic high soft tissue contrast of MR compared with that of CT.…”

“…Peripancreatic soft tissue invasion was diagnosed when the irregularly increased attenuation or signal intensity of the peripancreatic fat layer or spiculated border toward the peripancreatic fat layer on the pancreatic surface was seen (24). Choledochal or duodenal invasion was considered to be present if a suspected hypoattenuated or hypointense lesion directly invaded or reached the surface of the common bile duct and duodenum without evidence of intervening normal pancreatic parenchyma (24). Regional lymph nodes were considered positive when there was a short-axis diameter greater than 10 mm or there was necrosis regardless of its size (32).…”

“…However, with recent MR technological developments such as parallel acquisition imaging, high performance gradient phased array coils as well as rapid imaging sequences, MR developed into a useful imaging modality for the abdomen (21,22). Several previous studies have shown promising results using contrast-enhanced MRI using two-dimensional (2D) gradient-recalled echo (GRE) sequence for the detection and staging of pancreas cancer compared with those of CT (11,(23)(24)(25)(26), while some authors maintain that CT is superior to MRI (14,(27)(28)(29). Furthermore, recently developed three-dimensional (3D) GRE MR and 3D MRCP have led to improved visualization of the pancreatobiliary system by allowing higher spatial resolution and higher contrast resolution with reduced phase artifact and partial volume artifacts compared with 2D-GRE MRI or 2D MRCP (30).…”

CT and MR imaging patterns for pancreatic carcinoma invading the extrapancreatic neural plexus (Part II): Imaging of pancreatic carcinoma nerve invasion

“…Pancreatic carcinoma local invasion or extension has been shown as irregular signal intensity in the peripancreatic fat layer, spicular formations with hypointensity on the pancreatic surface, streaky and strand-like signal intensity structures, and mass forming in the peripancreatic fat space on �R imaging [23,[31][32][33] . 18 January 28, 2012|Volume 4|Issue 1| WJR|www.wjgnet.com …”

Enhanced primary tumor delineation in pancreatic adenocarcinoma using ultrasmall super paramagnetic iron oxide nanoparticle-ferumoxytol: an initial experience with histopathologic correlation

“…[13][14][15] MRI has also been proved equally efficacious in predicting vascular and nodal involvement. 16,17 CT, however, has limited capacity to characterize the nature of post-radiation soft tissue attenuation. 10 In fact, Katz et al, in their study of 129 patients with borderline resectable pancreatic carcinoma, concluded that radiographic downstaging was a rarity following neoadjuvant therapy.…”