Pancreatic Disease in Children and Adolescents

Abstract

Many childhood pancreatic disorders are rare, although they can represent significant and potentially severe disease. The spectrum of disease is very broad, ranging from the complex and bizarre congenital anomalies to the more typical acquired causes (e.g., drug-induced pancreatitis or trauma injury). Genetics appears to play a major role in many childhood pancreas diseases, unlike adults where alcohol is a major factor. Nevertheless, there are similarities, and most of the disorders discussed here can be found in both the pediatric and adult age groups. Some of these disorders may be evolving and may be seen in both young and older patients. Newer imaging modalities and therapeutic endoscopy continue to be studied, although their ultimate role and utility in children has yet to be fully elucidated.

Early Onset of Pediatric Autoimmune Pancreatitis at the US-Mexican Border

“…Pancreatic disease in children is uncommon but comprises of diverse etiologies and carries significant morbidity and mortality [1]. Although it is rare, acute pancreatitis is the most common pediatric pancreatic disease and recent literatures have shown an increasing incidence in children [1][2][3][4][5].…”

“…Pancreatic disease in children is uncommon but comprises of diverse etiologies and carries significant morbidity and mortality [1]. Although it is rare, acute pancreatitis is the most common pediatric pancreatic disease and recent literatures have shown an increasing incidence in children [1][2][3][4][5]. Autoimmune pancreatitis (AIP) in the pediatric population is thought to be an uncommon cause of acute and chronic pancreatitis but the true epidemiology remains unclear and more cases have been recently recognized [6][7][8][9].…”

Insuffisance pancréatique exocrine et syndrome de Turner : à propos d’un cas pédiatrique

“…Les causes les plus fréquentes chez l'enfant [1] sont la mucoviscidose, les traumatismes pancréa-tiques, les malformations, certains syndromes génétiques, la pancréatite chronique génétique ou auto-immune, mais éga-lement la maladie coeliaque [2]. Le syndrome de Turner (ST) caractérisé par le caryotype [45 X, 0] ne comporte habituellement pas d'atteinte pancréatique exocrine [3].…”