Pancreatic cancer-related pain: mechanism and management
Meijing Wu,
Afang Zhu,
Le Shen
Abstract:Pancreatic cancer related pain (PCRP) gains widespread attention for its high prevalence, extreme complexity, poor prognosis and decreased survival rate. Current treatment of PCRP remains unsatisfactory, since the underlying mechanism is not clear. The occurrence of PCRP is mainly related to the neurotropic nature of pancreatic cancer, and perineural invasion, neural remodeling and plasticity play important roles. Upon the understanding of PCRP mechanism, the management of PCRP is a multidisciplinary and multi… Show more
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