Pancreatic cancer: does irreversible electroporation improve the quality of life and the survival in local advanced pancreatic adenocarcinoma? Report of a pilot case

Braucci, Antonio; Niglio, Antonello; Molino, Carlo

doi:10.1016/j.pan.2013.04.152

Cited by 3 publications

(1 citation statement)

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“…In patients with borderline resectable and locally advanced pancreatic cancer, IRE was also identified as a valuable tool to offer consolidative disease control and symptom relief such as pain control and to support eradiation of the malignant lesion [19]. However, only few studies have evaluated the quality of life following IRE for pancreatic cancer [20]. In a recent study, 84 patients undergoing IRE for locally advanced pancreatic cancer were enrolled.…”

Section: Introductionmentioning

confidence: 99%

Computer Assistance in the Minimally Invasive Ablation Treatment of Pancreatic Cancer

Eigl¹,

Ανδρέου²,

Peterhans³

et al. 2021

Challenges in Pancreatic Cancer

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The insertion of ablation needles towards pancreatic tumors demands excellent anatomical knowledge and interdisciplinary skills from the medical professional. While the placement of a single needle next to the structures at risk surrounding the pancreas is considered a challenging task, irreversible electroporation requires multiple needles to be placed in parallel at a specific location. Minimally invasive procedures complicate the already ambitious procedure, yet the ablation method bears potential to increase the overall survival for patients with locally advanced pancreatic cancer. Current studies require more clinical evidence regarding the efficacy of irreversible electroporation in pancreatic cancer by means of randomized controlled, multicenter trials. However, the ablation treatment is currently applied in expert centers only, which is due to the complex task of the needle placement. Computer-assisted surgery has shown its potential in different fields of applications to improve the targeting of diseased tissue and the confidence of the medical professional. The application of computer-assisted needle navigation for pancreatic cancer ablation holds the prospect to make the procedure more reproducible and safer.

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Section: Introductionmentioning

confidence: 99%